Detalhe da pesquisa
1.
Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling.
Molecules
; 29(8)2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675561
2.
Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction.
Bioorg Med Chem
; 84: 117256, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37003157
3.
A novel de novo variant in POLR3B gene associated with a primary axonal involvement of the largest nerve fibers.
J Peripher Nerv Syst
; 28(4): 620-628, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37897416
4.
Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors.
Int J Mol Sci
; 24(11)2023 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298312
5.
Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing.
Int J Mol Sci
; 23(20)2022 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36293130
6.
Autoxidation Products of the Methanolic Extract of the Leaves of Combretum micranthum Exert Antiviral Activity against Tomato Brown Rugose Fruit Virus (ToBRFV).
Molecules
; 27(3)2022 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164024
7.
Labdane Diterpenoids from Salvia tingitana Etl. Synergize with Clindamycin against Methicillin-Resistant Staphylococcus aureus.
Molecules
; 26(21)2021 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771089
8.
Early onset demyelinating Charcot-Marie-Tooth disease caused by a novel in-frame isoleucine deletion in peripheral myelin protein 2.
J Peripher Nerv Syst
; 25(2): 102-106, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277537
9.
Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors.
Int J Mol Sci
; 21(21)2020 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33138251
10.
Recent Strategic Advances in CFTR Drug Discovery: An Overview.
Int J Mol Sci
; 21(7)2020 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32244346
11.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Molecules
; 25(13)2020 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605268
12.
Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB1 receptor ligand antagonists.
Bioorg Med Chem
; 26(1): 295-307, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229226
13.
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
Molecules
; 23(1)2018 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29316712
14.
Design and synthesis of 4,5,6,7-tetrahydro-1H-1,2-diazepin-7-one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors.
Bioorg Med Chem Lett
; 27(1): 24-29, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27890378
15.
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands.
J Enzyme Inhib Med Chem
; 32(1): 214-230, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28114832
16.
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles.
J Enzyme Inhib Med Chem
; 32(1): 375-402, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276287
17.
New arylsparteine derivatives as positive inotropic drugs.
J Enzyme Inhib Med Chem
; 32(1): 588-599, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28133984
18.
Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1.
Hum Mutat
; 37(11): 1202-1208, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27492805
19.
Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB2 receptor antagonists/inverse agonists.
Bioorg Med Chem
; 24(21): 5291-5301, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624523
20.
New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies.
Mol Divers
; 20(1): 77-92, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26290462