Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells.

Stelzner, Kathrin; Boyny, Aziza; Hertlein, Tobias; Sroka, Aneta; Moldovan, Adriana; Paprotka, Kerstin; Kessie, David; Mehling, Helene; Potempa, Jan; Ohlsen, Knut; Fraunholz, Martin J; Rudel, Thomas.

PLoS Pathog ; 17(9): e1009874, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34473800

2.

In or out: Phagosomal escape of Staphylococcus aureus.

Moldovan, Adriana; Fraunholz, Martin J.

Cell Microbiol ; 21(3): e12997, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30576050

3.

Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation.

Das, Sudip; Lindemann, Claudia; Young, Bernadette C; Muller, Julius; Österreich, Babett; Ternette, Nicola; Winkler, Ann-Cathrin; Paprotka, Kerstin; Reinhardt, Richard; Förstner, Konrad U; Allen, Elizabeth; Flaxman, Amy; Yamaguchi, Yuko; Rollier, Christine S; van Diemen, Pauline; Blättner, Sebastian; Remmele, Christian W; Selle, Martina; Dittrich, Marcus; Müller, Tobias; Vogel, Jörg; Ohlsen, Knut; Crook, Derrick W; Massey, Ruth; Wilson, Daniel J; Rudel, Thomas; Wyllie, David H; Fraunholz, Martin J.

Proc Natl Acad Sci U S A ; 113(22): E3101-10, 2016 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-27185949

4.

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes.

Blättner, Sebastian; Das, Sudip; Paprotka, Kerstin; Eilers, Ursula; Krischke, Markus; Kretschmer, Dorothee; Remmele, Christian W; Dittrich, Marcus; Müller, Tobias; Schuelein-Voelk, Christina; Hertlein, Tobias; Mueller, Martin J; Huettel, Bruno; Reinhardt, Richard; Ohlsen, Knut; Rudel, Thomas; Fraunholz, Martin J.

PLoS Pathog ; 12(9): e1005857, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27632173

5.

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections.

Tuchscherr, Lorena; Bischoff, Markus; Lattar, Santiago M; Noto Llana, Mariangeles; Pförtner, Henrike; Niemann, Silke; Geraci, Jennifer; Van de Vyver, Hélène; Fraunholz, Martin J; Cheung, Ambrose L; Herrmann, Mathias; Völker, Uwe; Sordelli, Daniel O; Peters, Georg; Löffler, Bettina.

PLoS Pathog ; 11(4): e1004870, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25923704

6.

Quantitative Proteomics Reveals the Dynamics of Protein Phosphorylation in Human Bronchial Epithelial Cells during Internalization, Phagosomal Escape, and Intracellular Replication of Staphylococcus aureus.

Richter, Erik; Harms, Manuela; Ventz, Katharina; Nölker, Rolf; Fraunholz, Martin J; Mostertz, Jörg; Hochgräfe, Falko.

J Proteome Res ; 15(12): 4369-4386, 2016 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-27762562

7.

Expression of Î´-toxin by Staphylococcus aureus mediates escape from phago-endosomes of human epithelial and endothelial cells in the presence of ß-toxin.

Giese, Bernd; Glowinski, Frithjof; Paprotka, Kerstin; Dittmann, Silvia; Steiner, Tobias; Sinha, Bhanu; Fraunholz, Martin J.

Cell Microbiol ; 13(2): 316-29, 2011 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-20946243

8.

Bacteriocyte dynamics during development of a holometabolous insect, the carpenter ant Camponotus floridanus.

Stoll, Sascha; Feldhaar, Heike; Fraunholz, Martin J; Gross, Roy.

BMC Microbiol ; 10: 308, 2010 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-21122115

9.

Intracellular Staphylococcus aureus Perturbs the Host Cell Ca²⁺ Homeostasis To Promote Cell Death.

Stelzner, Kathrin; Winkler, Ann-Cathrin; Liang, Chunguang; Boyny, Aziza; Ade, Carsten P; Dandekar, Thomas; Fraunholz, Martin J; Rudel, Thomas.

mBio ; 11(6)2020 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-33323513

10.

Staphylococcal alpha-toxin is not sufficient to mediate escape from phagolysosomes in upper-airway epithelial cells.

Giese, Bernd; Dittmann, Silvia; Paprotka, Kerstin; Levin, Katja; Weltrowski, Annett; Biehler, Diana; Lâm, Thiên-Trí; Sinha, Bhanu; Fraunholz, Martin J.

Infect Immun ; 77(9): 3611-25, 2009 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19564384

11.

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data.

Bahl, Amit; Brunk, Brian; Crabtree, Jonathan; Fraunholz, Martin J; Gajria, Bindu; Grant, Gregory R; Ginsburg, Hagai; Gupta, Dinesh; Kissinger, Jessica C; Labo, Philip; Li, Li; Mailman, Matthew D; Milgram, Arthur J; Pearson, David S; Roos, David S; Schug, Jonathan; Stoeckert, Christian J; Whetzel, Patricia.

Nucleic Acids Res ; 31(1): 212-5, 2003 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-12519984

12.

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished).

Bahl, Amit; Brunk, Brian; Coppel, Ross L; Crabtree, Jonathan; Diskin, Sharon J; Fraunholz, Martin J; Grant, Gregory R; Gupta, Dinesh; Huestis, Robert L; Kissinger, Jessica C; Labo, Philip; Li, Li; McWeeney, Shannon K; Milgram, Arthur J; Roos, David S; Schug, Jonathan; Stoeckert, Christian J.

Nucleic Acids Res ; 30(1): 87-90, 2002 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-11752262

13.

Systems biology in malaria research.

Fraunholz, Martin J.

Trends Parasitol ; 21(9): 393-5, 2005 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16043412

14.

Amino-terminal control of transgenic protein expression levels in Toxoplasma gondii.

Matrajt, Mariana; Nishi, Manami; Fraunholz, Martin J; Peter, Oliver; Roos, David S.

Mol Biochem Parasitol ; 120(2): 285-9, 2002 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-11897133

15.

PlasmoDB: exploring genomics and post-genomics data of the malaria parasite, Plasmodium falciparum.

Fraunholz, Martin J; Roos, David S.

Redox Rep ; 8(5): 317-20, 2003.

Artigo em Inglês | MEDLINE | ID: mdl-14962373

16.

Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast.

Ralph, Stuart A; van Dooren, Giel G; Waller, Ross F; Crawford, Michael J; Fraunholz, Martin J; Foth, Bernardo J; Tonkin, Christopher J; Roos, David S; McFadden, Geoffrey I.

Nat Rev Microbiol ; 2(3): 203-16, 2004 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-15083156

17.

Codon-improved fluorescent proteins in investigation of Staphylococcus aureus host pathogen interactions.

Paprotka, Kerstin; Giese, Bernd; Fraunholz, Martin J.

J Microbiol Methods ; 83(1): 82-6, 2010 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-20708040

18.

A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum.

Scholz, Matthias; Fraunholz, Martin J.

Genome Biol ; 9(5): R88, 2008.

Artigo em Inglês | MEDLINE | ID: mdl-18505551

19.

Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii.

Harb, Omar S; Chatterjee, Bithi; Fraunholz, Martin J; Crawford, Michael J; Nishi, Manami; Roos, David S.

Eukaryot Cell ; 3(3): 663-74, 2004 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-15189987

20.

Genome sequence of the human malaria parasite Plasmodium falciparum.

Gardner, Malcolm J; Hall, Neil; Fung, Eula; White, Owen; Berriman, Matthew; Hyman, Richard W; Carlton, Jane M; Pain, Arnab; Nelson, Karen E; Bowman, Sharen; Paulsen, Ian T; James, Keith; Eisen, Jonathan A; Rutherford, Kim; Salzberg, Steven L; Craig, Alister; Kyes, Sue; Chan, Man-Suen; Nene, Vishvanath; Shallom, Shamira J; Suh, Bernard; Peterson, Jeremy; Angiuoli, Sam; Pertea, Mihaela; Allen, Jonathan; Selengut, Jeremy; Haft, Daniel; Mather, Michael W; Vaidya, Akhil B; Martin, David M A; Fairlamb, Alan H; Fraunholz, Martin J; Roos, David S; Ralph, Stuart A; McFadden, Geoffrey I; Cummings, Leda M; Subramanian, G Mani; Mungall, Chris; Venter, J Craig; Carucci, Daniel J; Hoffman, Stephen L; Newbold, Chris; Davis, Ronald W; Fraser, Claire M; Barrell, Bart.

Nature ; 419(6906): 498-511, 2002 Oct 03.

Artigo em Inglês | MEDLINE | ID: mdl-12368864

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