Detalhe da pesquisa
1.
High-Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies Using Intact Mass Spectrometry.
Anal Chem
; 95(27): 10265-10278, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369001
2.
Chalcone Isomerase from Eubacterium ramulus Catalyzes the Ring Contraction of Flavanonols.
J Bacteriol
; 198(21): 2965-2974, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27551015
3.
En Route to New Therapeutic Options for Iron Overload Diseases: Matriptase-2 as a Target for Kunitz-Type Inhibitors.
Chembiochem
; 17(7): 595-604, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762582
4.
Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases.
Chemistry
; 22(2): 610-25, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26625703
5.
Phosphono Bisbenzguanidines as Irreversible Dipeptidomimetic Inhibitors and Activity-Based Probes of Matriptase-2.
Chemistry
; 22(25): 8525-35, 2016 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27214780
6.
Coumarin-thiazole and -oxadiazole derivatives: Synthesis, bioactivity and docking studies for aldose/aldehyde reductase inhibitors.
Bioorg Chem
; 68: 177-86, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27544072
7.
Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors.
Org Biomol Chem
; 13(41): 10310-23, 2015 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26307943
8.
Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors.
Bioorg Chem
; 61: 51-7, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26119990
9.
A coumarin-labeled vinyl sulfone as tripeptidomimetic activity-based probe for cysteine cathepsins.
Chembiochem
; 15(7): 955-9, 2014 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24648212
10.
Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis.
Bioorg Med Chem
; 22(21): 6163-73, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25257911
11.
Best practices for machine learning in antibody discovery and development.
Drug Discov Today
; 29(7): 104025, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38762089
12.
Computational Screening for mAb Colloidal Stability with Coarse-Grained, Molecular-Scale Simulations.
J Phys Chem B
; 128(6): 1515-1526, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315822
13.
Evaluation of molecular model-based discovery of ecto-5'-nucleotidase inhibitors on the basis of X-ray structures.
Bioorg Med Chem
; 21(21): 6616-22, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24012379
14.
Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.
Nat Commun
; 14(1): 3719, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349337
15.
Systematic identification and classification of three-dimensional activity cliffs.
J Chem Inf Model
; 52(6): 1490-8, 2012 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22612566
16.
An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics.
MAbs
; 13(1): 1955433, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34382900
17.
Identification of New Chromenone Derivatives as Cholinesterase Inhibitors and Molecular Docking Studies.
Med Chem
; 14(8): 809-817, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29473519
18.
Structural and Modeling Studies on ecto-5'-nucleotidase Aiding in Inhibitor Design.
Mini Rev Med Chem
; 15(1): 34-40, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25694084
19.
Comprehensive analysis of three-dimensional activity cliffs formed by kinase inhibitors with different binding modes and cliff mapping of structural analogues.
J Med Chem
; 58(1): 252-64, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25054653
20.
Current compound coverage of the kinome.
J Med Chem
; 58(1): 30-40, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25051177