Detalhe da pesquisa
1.
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates.
J Am Chem Soc
; 146(15): 10537-10549, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38567991
2.
Metabolomics Fingerprint Induced by the Intranigral Inoculation of Exogenous Human Alpha-Synuclein Oligomers in a Rat Model of Parkinson's Disease.
Int J Mol Sci
; 21(18)2020 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32937957
3.
Modeling Parkinson's Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers.
Int J Mol Sci
; 21(22)2020 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33198335
4.
Copper2+ Binding to α-Synuclein. Histidine50 Can Form a Ternary Complex with Cu2+ at the N-Terminus but Not a Macrochelate.
Inorg Chem
; 58(22): 15580-15589, 2019 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697492
5.
Molecular determinants of the interaction of EGCG with ordered and disordered proteins.
Biopolymers
; 109(10): e23117, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29603125
6.
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.
Biochemistry
; 56(9): 1177-1180, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28230968
7.
Conformational recognition of an intrinsically disordered protein.
Biophys J
; 106(8): 1771-9, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24739176
8.
Region-specific changes in gene expression are associated with cognitive deficits in the alpha-synuclein-induced model of Parkinson's disease: A transcriptomic profiling study.
Exp Neurol
; 372: 114651, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092188
9.
Metal interactions of α-synuclein probed by NMR amide-proton exchange.
Front Chem
; 11: 1167766, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37201129
10.
α-Synuclein and biological membranes: the danger of loving too much.
Chem Commun (Camb)
; 59(57): 8769-8778, 2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345454
11.
Thermal tuning of protein hydration in a hyperthermophilic enzyme.
Front Mol Biosci
; 9: 1037445, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36518847
12.
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes.
Front Mol Biosci
; 9: 981312, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36158582
13.
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat.
Protein Sci
; 31(9): e4396, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040267
14.
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation.
PNAS Nexus
; 1(5): pgac259, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36712380
15.
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex.
Cells
; 11(17)2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36078036
16.
Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson's Disease.
Neurotherapeutics
; 19(1): 305-324, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072912
17.
Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins.
Life (Basel)
; 11(2)2021 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33673214
18.
Membrane Interactions and Toxicity by Misfolded Protein Oligomers.
Front Cell Dev Biol
; 9: 642623, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33791300
19.
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition.
Nat Commun
; 12(1): 927, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568632
20.
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.
Front Cell Dev Biol
; 9: 552549, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33829010