Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition.

Hamaguchi, Wataru; Masuda, Naoyuki; Miyamoto, Satoshi; Shiina, Yasuhiro; Kikuchi, Shigetoshi; Mihara, Takuma; Moriguchi, Hiroyuki; Fushiki, Hiroshi; Murakami, Yoshihiro; Amano, Yasushi; Honbou, Kazuya; Hattori, Kouji.

Bioorg Med Chem ; 23(2): 297-313, 2015 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-25515954

2.

Synthesis and Preliminary Evaluation of an ¹⁸F-labeled Oleate Analog to Image Fatty Acid Beta-Oxidation in the Absence of Metabolic Defluorination.

Murakami, Yoshihiro; Fujita, Yuji; Fushiki, Hiroshi.

Mol Imaging Biol ; 25(3): 495-502, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36220956

3.

Preclinical Development and Validation of ASP5354: A Near-Infrared Fluorescent Agent for Intraoperative Ureter Visualization.

Fushiki, Hiroshi; Yoshikawa, Tomoaki; Matsuda, Toshihiro; Sato, Takeshi; Suwa, Akira.

Mol Imaging Biol ; 25(1): 74-84, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-33977418

4.

A novel anti-NGF PEGylated Fab' provides analgesia with lower risk of adverse effects.

Koya, Yukari; Tanaka, Hirotsugu; Yoshimi, Eiji; Takeshita, Nobuaki; Morita, Shuji; Morio, Hiroki; Mori, Kanako; Fushiki, Hiroshi; Kamohara, Masazumi.

MAbs ; 15(1): 2149055, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-36458900

5.

Selective M3 muscarinic receptor antagonist inhibits small-cell lung carcinoma growth in a mouse orthotopic xenograft model.

Ami, Nozomi; Koga, Kazumi; Fushiki, Hiroshi; Ueno, Yoko; Ogino, Yoshio; Ohta, Hisashi.

J Pharmacol Sci ; 116(1): 81-8, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21512307

6.

In vivo imaging of obesity-induced inflammation in adipose tissue.

Fushiki, Hiroshi; Hayakawa, Yoshihiro; Gomori, Akira; Seo, Toru; Tewari, Shruti; Ozaki, Satoshi; Yoshimoto, Ryo.

Biochem Biophys Res Commun ; 391(1): 674-8, 2010 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-19961831

7.

Quantification of mouse pulmonary cancer models by microcomputed tomography imaging.

Fushiki, Hiroshi; Kanoh-Azuma, Tomoko; Katoh, Masahiro; Kawabata, Ken; Jiang, Jian; Tsuchiya, Nozomi; Satow, Akio; Tamai, Yoshitaka; Hayakawa, Yoshihiro.

Cancer Sci ; 100(8): 1544-9, 2009 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-19459854

8.

Correction to: Synthesis and Preliminary Evaluation of an ¹⁸F-Labeled Oleate Analog to Image Fatty Acid Beta-Oxidation in the Absence of Metabolic Defluorination.

Murakami, Yoshihiro; Fujita, Yuji; Fushiki, Hiroshi.

Mol Imaging Biol ; 25(3): 503, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-36380014

9.

Preclinical Evaluation of an Anti-Nectin-4 ImmunoPET Reagent in Tumor-Bearing Mice and Biodistribution Studies in Cynomolgus Monkeys.

Campbell, Dean O; Noda, Akihiro; Verlinsky, Alla; Snyder, Josh; Fujita, Yuji; Murakami, Yoshihiro; Fushiki, Hiroshi; Miyoshi, Sosuke; Lacayo, Sergio; Cabral, Edward; Yang, Peng; Stover, David R; Joseph, Ingrid B J K.

Mol Imaging Biol ; 18(5): 768-75, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27122234

10.

[A trial of biweekly paclitaxel administration in consideration of QOL for advanced or recurrent gynecologic cancer].

Fushiki, Hiroshi; Yoshimoto, Hideo; Ikoma, Tomomi; Ota, Satoru.

Gan To Kagaku Ryoho ; 32(5): 691-3, 2005 May.

Artigo em Japonês | MEDLINE | ID: mdl-15918575

11.

PET imaging for tyrosine kinase inhibitor (TKI) biodistribution in mice.

Fushiki, Hiroshi; Murakami, Yoshihiro; Miyoshi, Sosuke; Nishimura, Shintaro.

Methods Mol Biol ; 1219: 199-206, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-25308271

12.

Investigation of Mechanisms for MK-801-Induced Neurotoxicity Utilizing Metabolomic Approach.

Kuroda, Kanae; Suzumura, Kenichi; Shirakawa, Takafumi; Hiraishi, Tomoko; Nakahara, Yutaka; Fushiki, Hiroshi; Honda, Sokichi; Naraoka, Hitoshi; Miyoshi, Sosuke; Aoki, Yoshinobu.

Toxicol Sci ; 146(2): 344-53, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26018836

13.

A free radical initiator, 2,2'-azobis (2-aminopropane) dihydrochloride enhances hyperthermia-induced apoptosis in human uterine cervical cancer cell lines.

Yuki, Hiroyoshi; Kondo, Takashi; Zhao, Qing-Li; Fujiwara, Yoshisada; Tanabe, Kiyoshi; Ogawa, Ryohei; Nakashima, Akitoshi; Fushiki, Hiroshi; Fujimura, Masaki; Saito, Shigeru.

Free Radic Res ; 37(6): 631-43, 2003 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12868490

14.

[A case of uterine endometrial cancer with lung metastases improved by various treatments including taxane].

Fushiki, Hiroshi; Yoshimoto, Hideo; Maeda, Eiko.

Gan To Kagaku Ryoho ; 30(8): 1183-6, 2003 Aug.

Artigo em Japonês | MEDLINE | ID: mdl-12938278

15.

[Apoptosis as a measure of chemosensitivity to anti-cancer drugs in gynecological cancer].

Fushiki, Hiroshi; Yuuki, Hiroyoshi; Nakashima, Akitoshi; Fujimura, Masaki; Saito, Shigeru; Izumi, Rikuichi.

Gan To Kagaku Ryoho ; 29(2): 215-9, 2002 Feb.

Artigo em Japonês | MEDLINE | ID: mdl-11865626

16.

The selective anaplastic lymphoma receptor tyrosine kinase inhibitor ASP3026 induces tumor regression and prolongs survival in non-small cell lung cancer model mice.

Mori, Masamichi; Ueno, Yoko; Konagai, Satoshi; Fushiki, Hiroshi; Shimada, Itsuro; Kondoh, Yutaka; Saito, Rika; Mori, Kenichi; Shindou, Nobuaki; Soga, Takatoshi; Sakagami, Hideki; Furutani, Takashi; Doihara, Hitoshi; Kudoh, Masafumi; Kuromitsu, Sadao.

Mol Cancer Ther ; 13(2): 329-40, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24419060

17.

Pre-clinical validation of orthotopically-implanted pulmonary tumor by imaging with 18F-fluorothymidine-positron emission tomography/computed tomography.

Fushiki, Hiroshi; Miyoshi, Sosuke; Noda, Akihiro; Murakami, Yoshihiro; Sasaki, Hiroshi; Jitsuoka, Makoto; Mitsuoka, Keisuke; Matsunari, Ichiro; Nishimura, Shintaro.

Anticancer Res ; 33(11): 4741-9, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24222108

18.

Brain penetration of telmisartan, a unique centrally acting angiotensin II type 1 receptor blocker, studied by PET in conscious rhesus macaques.

Noda, Akihiro; Fushiki, Hiroshi; Murakami, Yoshihiro; Sasaki, Hiroshi; Miyoshi, Sosuke; Kakuta, Hirotoshi; Nishimura, Shintaro.

Nucl Med Biol ; 39(8): 1232-5, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22890047

19.

[Ovarian remnant syndrome].

Fushiki, Hiroshi.

Nihon Rinsho ; Suppl 2: 468-70, 2006 Jun 28.

Artigo em Japonês | MEDLINE | ID: mdl-16817444

20.

YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer.

Yamanaka, Kentaro; Nakata, Mari; Kaneko, Naoki; Fushiki, Hiroshi; Kita, Aya; Nakahara, Takahito; Koutoku, Hiroshi; Sasamata, Masao.

Int J Oncol ; 39(3): 569-75, 2011 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-21674125

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