Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Step-in dosing of bosutinib in pts with chronic phase chronic myeloid leukemia (CML) after second-generation tyrosine kinase inhibitor (TKI) therapy: results of the Bosutinib Dose Optimization (BODO) Study.

Isfort, Susanne; Manz, Kirsi; Teichmann, Lino L; Crysandt, Martina; Burchert, Andreas; Hochhaus, Andreas; Saussele, Susanne; Kiani, Alexander; Göthert, Joachim R; Illmer, Thomas; Schafhausen, Philippe; Al-Ali, Haifa Kathrin; Stegelmann, Frank; Hänel, Mathias; Pfeiffer, Tim; Giagounidis, Aristoteles; Franke, Georg-Nikolaus; Koschmieder, Steffen; Fabarius, Alice; Ernst, Thomas; Warnken-Uhlich, Mareille; Wolber, Uta; Kohn, Denise; Pfirrmann, Markus; Wolf, Dominik; Brümmendorf, Tim H.

Ann Hematol ; 102(10): 2741-2752, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37592092

2.

Emergence, Transmission, and Potential Therapeutic Targets for the COVID-19 Pandemic Associated with the SARS-CoV-2.

Patil, Ashwini M; Göthert, Joachim R; Khairnar, Vishal.

Cell Physiol Biochem ; 54(4): 767-790, 2020 Aug 25.

Artigo em Inglês | MEDLINE | ID: mdl-32830930

3.

Bypassing T cell 'exhaustion'.

Göthert, Joachim R.

Nat Immunol ; 14(11): 1114-6, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24145784

4.

Identification of a new VHL exon and complex splicing alterations in familial erythrocytosis or von Hippel-Lindau disease.

Lenglet, Marion; Robriquet, Florence; Schwarz, Klaus; Camps, Carme; Couturier, Anne; Hoogewijs, David; Buffet, Alexandre; Knight, Samantha J L; Gad, Sophie; Couvé, Sophie; Chesnel, Franck; Pacault, Mathilde; Lindenbaum, Pierre; Job, Sylvie; Dumont, Solenne; Besnard, Thomas; Cornec, Marine; Dreau, Helene; Pentony, Melissa; Kvikstad, Erika; Deveaux, Sophie; Burnichon, Nelly; Ferlicot, Sophie; Vilaine, Mathias; Mazzella, Jean-Michaël; Airaud, Fabrice; Garrec, Céline; Heidet, Laurence; Irtan, Sabine; Mantadakis, Elpis; Bouchireb, Karim; Debatin, Klaus-Michael; Redon, Richard; Bezieau, Stéphane; Bressac-de Paillerets, Brigitte; Teh, Bin Tean; Girodon, François; Randi, Maria-Luigia; Putti, Maria Caterina; Bours, Vincent; Van Wijk, Richard; Göthert, Joachim R; Kattamis, Antonis; Janin, Nicolas; Bento, Celeste; Taylor, Jenny C; Arlot-Bonnemains, Yannick; Richard, Stéphane; Gimenez-Roqueplo, Anne-Paule; Cario, Holger.

Blood ; 132(5): 469-483, 2018 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-29891534

5.

Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib.

Bornemann, Lea; Schuster, Marc; Schmitz, Saskia; Sobczak, Charlyn; Bessen, Clara; Merz, Simon F; Jöckel, Karl-Heinz; Haverkamp, Thomas; Gunzer, Matthias; Göthert, Joachim R.

BMC Cancer ; 20(1): 650, 2020 Jul 13.

Artigo em Inglês | MEDLINE | ID: mdl-32660441

6.

Pathological manifestations of Farber disease in a new mouse model.

Beckmann, Nadine; Kadow, Stephanie; Schumacher, Fabian; Göthert, Joachim R; Kesper, Stefanie; Draeger, Annette; Schulz-Schaeffer, Walter J; Wang, Jiang; Becker, Jan U; Kramer, Melanie; Kühn, Claudine; Kleuser, Burkhard; Becker, Katrin Anne; Gulbins, Erich; Carpinteiro, Alexander.

Biol Chem ; 399(10): 1183-1202, 2018 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-29908121

7.

Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

Hasenberg, Anja; Hasenberg, Mike; Männ, Linda; Neumann, Franziska; Borkenstein, Lars; Stecher, Manuel; Kraus, Andreas; Engel, Daniel R; Klingberg, Anika; Seddigh, Pegah; Abdullah, Zeinab; Klebow, Sabrina; Engelmann, Swen; Reinhold, Annegret; Brandau, Sven; Seeling, Michaela; Waisman, Ari; Schraven, Burkhart; Göthert, Joachim R; Nimmerjahn, Falk; Gunzer, Matthias.

Nat Methods ; 12(5): 445-52, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25775045

8.

The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis.

Schoedel, Kristina B; Morcos, Mina N F; Zerjatke, Thomas; Roeder, Ingo; Grinenko, Tatyana; Voehringer, David; Göthert, Joachim R; Waskow, Claudia; Roers, Axel; Gerbaulet, Alexander.

Blood ; 128(19): 2285-2296, 2016 11 10.

Artigo em Inglês | MEDLINE | ID: mdl-27357698

9.

Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice.

von Wnuck Lipinski, Karin; Sattler, Katherine; Peters, Susann; Weske, Sarah; Keul, Petra; Klump, Hannes; Heusch, Gerd; Göthert, Joachim R; Levkau, Bodo.

J Immunol ; 196(4): 1655-65, 2016 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-26800876

10.

Endothelial ß-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis.

Tran, Khiem A; Zhang, Xianming; Predescu, Dan; Huang, Xiaojia; Machado, Roberto F; Göthert, Joachim R; Malik, Asrar B; Valyi-Nagy, Tibor; Zhao, You-Yang.

Circulation ; 133(2): 177-86, 2016 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-26538583

11.

Regulation of Arthritis Severity by the Acid Sphingomyelinase.

Beckmann, Nadine; Becker, Katrin Anne; Walter, Silke; Becker, Jan U; Kramer, Melanie; Hessler, Gabriele; Weber, Stefanie; Göthert, Joachim R; Fassbender, Klaus; Gulbins, Erich; Carpinteiro, Alexander.

Cell Physiol Biochem ; 43(4): 1460-1471, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-29035882

12.

Deficiency in lymphotoxin ß receptor protects from atherosclerosis in apoE-deficient mice.

Grandoch, Maria; Feldmann, Kathrin; Göthert, Joachim R; Dick, Lena S; Homann, Susanne; Klatt, Christina; Bayer, Julia K; Waldheim, Jan N; Rabausch, Berit; Nagy, Nadine; Oberhuber, Alexander; Deenen, René; Köhrer, Karl; Lehr, Stefan; Homey, Bernhard; Pfeffer, Klaus; Fischer, Jens W.

Circ Res ; 116(8): e57-68, 2015 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-25740843

13.

Hemovascular Progenitors in the Kidney Require Sphingosine-1-Phosphate Receptor 1 for Vascular Development.

Hu, Yan; Li, Minghong; Göthert, Joachim R; Gomez, R Ariel; Sequeira-Lopez, Maria Luisa S.

J Am Soc Nephrol ; 27(7): 1984-95, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-26534925

14.

Involvement of Toso in activation of monocytes, macrophages, and granulocytes.

Lang, Karl S; Lang, Philipp A; Meryk, Andreas; Pandyra, Aleksandra A; Boucher, Louis-Martin; Pozdeev, Vitaly I; Tusche, Michael W; Göthert, Joachim R; Haight, Jillian; Wakeham, Andrew; You-Ten, Annick J; McIlwain, David R; Merches, Katja; Khairnar, Vishal; Recher, Mike; Nolan, Garry P; Hitoshi, Yasumichi; Funkner, Pauline; Navarini, Alexander A; Verschoor, Admar; Shaabani, Namir; Honke, Nadine; Penn, Linda Z; Ohashi, Pamela S; Häussinger, Dieter; Lee, Kyeong-Hee; Mak, Tak W.

Proc Natl Acad Sci U S A ; 110(7): 2593-8, 2013 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-23359703

15.

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis.

Ey, Birgit; Eyking, Annette; Klepak, Magdalena; Salzman, Nita H; Göthert, Joachim R; Rünzi, Michael; Schmid, Kurt W; Gerken, Guido; Podolsky, Daniel K; Cario, Elke.

J Immunol ; 190(11): 5676-88, 2013 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-23636052

16.

Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses.

Herz, Josephine; Hagen, Sabine I; Bergmüller, Eileen; Sabellek, Pascal; Göthert, Joachim R; Buer, Jan; Hansen, Wiebke; Hermann, Dirk M; Doeppner, Thorsten R.

Neurobiol Dis ; 62: 456-68, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24184800

17.

Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries.

Retailleau, Kevin; Toutain, Bertrand; Galmiche, Guillaume; Fassot, Céline; Sharif-Naeini, Reza; Kauffenstein, Gilles; Mericskay, Mathias; Duprat, Fabrice; Grimaud, Linda; Merot, Jean; Lardeux, Aurelie; Pizard, Anne; Baudrie, Véronique; Jeunemaitre, Xavier; Feil, Robert; Göthert, Joachim R; Lacolley, Patrick; Henrion, Daniel; Li, Zhenlin; Loufrani, Laurent.

Arterioscler Thromb Vasc Biol ; 33(2): 339-46, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23264443

18.

Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.

Courtial, Nadine; Smink, Jeske J; Kuvardina, Olga N; Leutz, Achim; Göthert, Joachim R; Lausen, Jörn.

FASEB J ; 26(2): 523-32, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21990371

19.

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.

Flümann, Ruth; Hansen, Julia; Pelzer, Benedikt W; Nieper, Pascal; Lohmann, Tim; Kisis, Ilmars; Riet, Tobias; Kohlhas, Viktoria; Nguyen, Phuong-Hien; Peifer, Martin; Abedpour, Nima; Bosco, Graziella; Thomas, Roman K; Kochanek, Moritz; Knüfer, Jacqueline; Jonigkeit, Lorenz; Beleggia, Filippo; Holzem, Alessandra; Büttner, Reinhard; Lohneis, Philipp; Meinel, Jörn; Ortmann, Monika; Persigehl, Thorsten; Hallek, Michael; Calado, Dinis Pedro; Chmielewski, Markus; Klein, Sebastian; Göthert, Joachim R; Chapuy, Bjoern; Zevnik, Branko; Wunderlich, F Thomas; von Tresckow, Bastian; Jachimowicz, Ron D; Melnick, Ari M; Reinhardt, Hans Christian; Knittel, Gero.

Blood Cancer Discov ; 4(1): 78-97, 2023 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-36346827

20.

BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.

Schemionek, Mirle; Elling, Christian; Steidl, Ulrich; Bäumer, Nicole; Hamilton, Ashley; Spieker, Tilmann; Göthert, Joachim R; Stehling, Martin; Wagers, Amy; Huettner, Claudia S; Tenen, Daniel G; Tickenbrock, Lara; Berdel, Wolfgang E; Serve, Hubert; Holyoake, Tessa L; Müller-Tidow, Carsten; Koschmieder, Steffen.

Blood ; 115(16): 3185-95, 2010 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-20053753

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