Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

An in vivo neuroimmune organoid model to study human microglia phenotypes.

Schafer, Simon T; Mansour, Abed AlFatah; Schlachetzki, Johannes C M; Pena, Monique; Ghassemzadeh, Saeed; Mitchell, Lisa; Mar, Amanda; Quang, Daphne; Stumpf, Sarah; Ortiz, Irene Santisteban; Lana, Addison J; Baek, Clara; Zaghal, Raghad; Glass, Christopher K; Nimmerjahn, Axel; Gage, Fred H.

Cell ; 186(10): 2111-2126.e20, 2023 05 11.

Artigo em Inglês | MEDLINE | ID: mdl-37172564

2.

A Mechanism for Somatic Brain Mosaicism.

Weissman, Irving L; Gage, Fred H.

Cell ; 164(4): 593-5, 2016 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-26871622

3.

Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior.

Gonçalves, J Tiago; Schafer, Simon T; Gage, Fred H.

Cell ; 167(4): 897-914, 2016 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-27814520

4.

Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest.

Prescott, Sara L; Srinivasan, Rajini; Marchetto, Maria Carolina; Grishina, Irina; Narvaiza, Iñigo; Selleri, Licia; Gage, Fred H; Swigut, Tomek; Wysocka, Joanna.

Cell ; 163(1): 68-83, 2015 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-26365491

5.

Primate-specific ORF0 contributes to retrotransposon-mediated diversity.

Denli, Ahmet M; Narvaiza, Iñigo; Kerman, Bilal E; Pena, Monique; Benner, Christopher; Marchetto, Maria C N; Diedrich, Jolene K; Aslanian, Aaron; Ma, Jiao; Moresco, James J; Moore, Lynne; Hunter, Tony; Saghatelian, Alan; Gage, Fred H.

Cell ; 163(3): 583-93, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496605

6.

A nomenclature consensus for nervous system organoids and assembloids.

PaÈca, Sergiu P; Arlotta, Paola; Bateup, Helen S; Camp, J Gray; Cappello, Silvia; Gage, Fred H; Knoblich, Jürgen A; Kriegstein, Arnold R; Lancaster, Madeline A; Ming, Guo-Li; Muotri, Alysson R; Park, In-Hyun; Reiner, Orly; Song, Hongjun; Studer, Lorenz; Temple, Sally; Testa, Giuseppe; Treutlein, Barbara; Vaccarino, Flora M.

Nature ; 609(7929): 907-910, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36171373

7.

The role of retrotransposable elements in ageing and age-associated diseases.

Gorbunova, Vera; Seluanov, Andrei; Mita, Paolo; McKerrow, Wilson; Fenyö, David; Boeke, Jef D; Linker, Sara B; Gage, Fred H; Kreiling, Jill A; Petrashen, Anna P; Woodham, Trenton A; Taylor, Jackson R; Helfand, Stephen L; Sedivy, John M.

Nature ; 596(7870): 43-53, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34349292

8.

Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases.

Mertens, Jerome; Reid, Dylan; Lau, Shong; Kim, Yongsung; Gage, Fred H.

Annu Rev Genet ; 52: 271-293, 2018 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-30208291

9.

Novel correlative analysis identifies multiple genomic variations impacting ASD with macrocephaly.

Fu, Chen; Ngo, Justine; Zhang, Shanshan; Lu, Leina; Miron, Alexander; Schafer, Simon; Gage, Fred H; Jin, Fulai; Schumacher, Fredrick R; Wynshaw-Boris, Anthony.

Hum Mol Genet ; 32(10): 1589-1606, 2023 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-36519762

10.

Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis.

Bedrosian, Tracy A; Houtman, Judith; Eguiguren, Juan Sebastian; Ghassemzadeh, Saeed; Rund, Nicole; Novaresi, Nicole M; Hu, Lauren; Parylak, Sarah L; Denli, Ahmet M; Randolph-Moore, Lynne; Namba, Takashi; Gage, Fred H; Toda, Tomohisa.

EMBO J ; 40(3): e105819, 2021 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-33300615

11.

Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures.

Podvin, Sonia; Jones, Jeffrey; Kang, Austin; Goodman, Ryan; Reed, Patrick; Lietz, Christopher B; Then, Joshua; Lee, Kelly C; Eyler, Lisa T; Jeste, Dilip V; Gage, Fred H; Hook, Vivian.

Mol Psychiatry ; 2024 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-38302561

12.

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission.

Stern, Shani; Zhang, Lei; Wang, Meiyan; Wright, Rebecca; Rosh, Idan; Hussein, Yara; Stern, Tchelet; Choudhary, Ashwani; Tripathi, Utkarsh; Reed, Patrick; Sadis, Hagit; Nayak, Ritu; Shemen, Aviram; Agarwal, Karishma; Cordeiro, Diogo; Peles, David; Hang, Yuqing; Mendes, Ana P D; Baul, Tithi D; Roth, Julien G; Coorapati, Shashank; Boks, Marco P; McCombie, W Richard; Hulshoff Pol, Hilleke; Brennand, Kristen J; Réthelyi, János M; Kahn, René S; Marchetto, Maria C; Gage, Fred H.

Mol Psychiatry ; 2024 May 04.

Artigo em Inglês | MEDLINE | ID: mdl-38704507

13.

Mechanisms underlying inflammation in neurodegeneration.

Glass, Christopher K; Saijo, Kaoru; Winner, Beate; Marchetto, Maria Carolina; Gage, Fred H.

Cell ; 140(6): 918-34, 2010 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-20303880

14.

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells.

Marchetto, Maria C N; Carromeu, Cassiano; Acab, Allan; Yu, Diana; Yeo, Gene W; Mu, Yangling; Chen, Gong; Gage, Fred H; Muotri, Alysson R.

Cell ; 143(4): 527-39, 2010 Nov 12.

Artigo em Inglês | MEDLINE | ID: mdl-21074045

15.

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.

Farrelly, Lorna A; Thompson, Robert E; Zhao, Shuai; Lepack, Ashley E; Lyu, Yang; Bhanu, Natarajan V; Zhang, Baichao; Loh, Yong-Hwee E; Ramakrishnan, Aarthi; Vadodaria, Krishna C; Heard, Kelly J; Erikson, Galina; Nakadai, Tomoyoshi; Bastle, Ryan M; Lukasak, Bradley J; Zebroski, Henry; Alenina, Natalia; Bader, Michael; Berton, Olivier; Roeder, Robert G; Molina, Henrik; Gage, Fred H; Shen, Li; Garcia, Benjamin A; Li, Haitao; Muir, Tom W; Maze, Ian.

Nature ; 567(7749): 535-539, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30867594

16.

Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients.

Mizrahi, Liron; Choudhary, Ashwani; Ofer, Polina; Goldberg, Gabriela; Milanesi, Elena; Kelsoe, John R; Gurwitz, David; Alda, Martin; Gage, Fred H; Stern, Shani.

Mol Psychiatry ; 28(10): 4280-4293, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37488168

17.

Induced pluripotent stem cells: the new patient?

Bellin, Milena; Marchetto, Maria C; Gage, Fred H; Mummery, Christine L.

Nat Rev Mol Cell Biol ; 13(11): 713-26, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23034453

18.

SnapShot: adult hippocampal neurogenesis.

Vadodaria, Krishna C; Gage, Fred H.

Cell ; 156(5): 1114-1114.e1, 2014 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-24581504

19.

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death.

Saijo, Kaoru; Winner, Beate; Carson, Christian T; Collier, Jana G; Boyer, Leah; Rosenfeld, Michael G; Gage, Fred H; Glass, Christopher K.

Cell ; 137(1): 47-59, 2009 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-19345186

20.

The Rhox gene cluster suppresses germline LINE1 transposition.

Tan, Kun; Kim, Matthew E; Song, Hye-Won; Skarbrevik, David; Babajanian, Eric; Bedrosian, Tracy A; Gage, Fred H; Wilkinson, Miles F.

Proc Natl Acad Sci U S A ; 118(23)2021 06 08.

Artigo em Inglês | MEDLINE | ID: mdl-34083437

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