Detalhe da pesquisa
1.
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.
Nature
; 575(7781): 217-223, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31666701
2.
Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment.
Clin Exp Rheumatol
; 37(6): 906-914, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30789152
3.
Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function.
J Immunol
; 196(2): 573-85, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673135
4.
Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease.
J Pharmacol Exp Ther
; 345(2): 225-38, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23475901
5.
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Front Pharmacol
; 10: 51, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30837866
6.
Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey.
J Immunotoxicol
; 12(2): 164-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990272
7.
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.
J Med Chem
; 58(17): 6784-802, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26288216
8.
Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain.
Pain
; 149(1): 33-49, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167427
9.
Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hosts.
Int J Cancer
; 103(4): 501-7, 2003 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12478666
10.
The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.
Nat Immunol
; 4(9): 899-906, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12925852