Detalhe da pesquisa
1.
Trityl Cation-Catalyzed Hosomi-Sakurai Reaction of Allylsilane with ß,γ-Unsaturated α-Ketoester to Form γ,γ-Disubstituted α-Ketoesters.
Molecules
; 27(15)2022 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897907
2.
Intrathecal administration of a novel siRNA modality extends survival and improves motor function in the SOD1G93A ALS mouse model.
Mol Ther Nucleic Acids
; 35(1): 102147, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38435120
3.
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver.
Nat Biomed Eng
; 6(2): 157-167, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35190679
4.
Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands.
Bioeng Transl Med
; 5(3): e10161, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758781
5.
Increased PIP3 activity blocks nanoparticle mRNA delivery.
Sci Adv
; 6(30): eaba5672, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32743074
6.
Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery.
Adv Mater
; 32(1): e1904905, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31743531
7.
Cell Subtypes Within the Liver Microenvironment Differentially Interact with Lipid Nanoparticles.
Cell Mol Bioeng
; 12(5): 389-397, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719922
8.
Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.
Adv Mater
; 31(41): e1902251, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31465135
9.
Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses.
Adv Mater
; 31(14): e1807748, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30748040
10.
Prins cyclization of bis(silyl) homoallylic alcohols to form 2,6-cis-tetrahydropyrans containing a geometrically defined exocyclic vinylsilane: efficient synthesis of ring B of the bryostatins.
Angew Chem Int Ed Engl
; 51(22): 5367-70, 2012 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22504783
11.
Tunable reactivity of geminal bis(silyl) enol derivatives leading to selective exo-IEDDA or Sakurai allylation with a ß,γ-unsaturated ketoester.
Chem Commun (Camb)
; 52(66): 10137-40, 2016 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27457733
12.
Visible light-promoted radical cyclization of silicon-tethered alkyl iodide and phenyl alkyne. An efficient approach to synthesize benzosilolines.
Chem Commun (Camb)
; 52(36): 6189-92, 2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27078741
13.
1,4-Hydroiodination of dienyl alcohols with TMSI to form homoallylic alcohols containing a multisubstituted Z-alkene and application to Prins cyclization.
Org Lett
; 17(8): 1846-9, 2015 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825952