Detalhe da pesquisa
1.
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness.
Nature
; 537(7619): 229-233, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27501246
2.
Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.
Nat Methods
; 15(11): 941-946, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297964
3.
Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem J
; 430(3): 425-37, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20632993
4.
Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology.
J Med Chem
; 64(8): 4857-4869, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33821636
5.
Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors.
ACS Med Chem Lett
; 12(12): 1912-1919, 2021 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34917254
6.
Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.
ACS Med Chem Lett
; 11(4): 558-565, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292564
7.
Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.
J Med Chem
; 63(19): 10773-10781, 2020 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667203
8.
Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett
; 8(10): 1048-1053, 2017 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057049
9.
Pectin induces apoptosis in human prostate cancer cells: correlation of apoptotic function with pectin structure.
Glycobiology
; 17(8): 805-19, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17513886
10.
Exo-oligosaccharides of Rhizobium sp. strain NGR234 are required for symbiosis with various legumes.
J Bacteriol
; 188(17): 6168-78, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16923883
11.
Involvement of exo5 in production of surface polysaccharides in Rhizobium leguminosarum and its role in nodulation of Vicia sativa subsp. nigra.
J Bacteriol
; 186(19): 6617-25, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15375143