Detalhe da pesquisa
1.
Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol.
J Biol Chem
; 290(8): 4573-4589, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552479
2.
Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors.
Bioorg Med Chem Lett
; 25(20): 4399-404, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26372653
3.
In vitro and in vivo characterization of the JAK1 selectivity of upadacitinib (ABT-494).
BMC Rheumatol
; 2: 23, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30886973