Detalhe da pesquisa
1.
A novel aminopeptidase N/CD13 inhibitor selectively targets an endothelial form of CD13 after coupling to proteins.
Cell Mol Life Sci
; 81(1): 68, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38289472
2.
Structural basis for PHDVC5HCHNSD1-C2HRNizp1 interaction: implications for Sotos syndrome.
Nucleic Acids Res
; 44(7): 3448-63, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26896805
3.
Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing.
Adv Funct Mater
; 27(36)2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28979182
4.
Dissecting intrinsic and ligand-induced structural communication in the ß3 headpiece of integrins.
Biochim Biophys Acta Gen Subj
; 1861(9): 2367-2381, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28549920
5.
Identification of TMPRSS6 cleavage sites of hemojuvelin.
J Cell Mol Med
; 19(4): 879-88, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25704252
6.
Metadynamics Simulations Rationalise the Conformational Effects Induced by N-Methylation of RGD Cyclic Hexapeptides.
Chemistry
; 21(40): 14165-70, 2015 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248541
7.
NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions.
Adv Exp Med Biol
; 805: 271-304, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24446366
8.
The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12.
Nat Commun
; 15(1): 1201, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38331917
9.
Molecular dynamics reveal that isoDGR-containing cyclopeptides are true αvß3 antagonists unable to promote integrin allostery and activation.
Angew Chem Int Ed Engl
; 51(31): 7702-5, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22718573
10.
Solution Structure of the BPSL1445 Protein of Burkholderia pseudomallei Reveals the SYLF Domain Three-Dimensional Fold.
ACS Chem Biol
; 17(1): 230-239, 2022 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34968022
11.
In silico derived small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor.
Comput Struct Biotechnol J
; 18: 4082-4092, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33363704
12.
Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.
Biochim Biophys Acta Gen Subj
; 1863(2): 456-465, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30465816
13.
A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvß6 and αvß8.
Chem Commun (Camb)
; 55(98): 14777-14780, 2019 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31755501
14.
Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009.
mSphere
; 3(2)2018 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29624498
15.
Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to αvß3 without Promoting Integrin Allosteric Activation.
J Med Chem
; 61(17): 7474-7485, 2018 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29883545
16.
A persulfidation-based mechanism controls aquaporin-8 conductance.
Sci Adv
; 4(5): eaar5770, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29732408
17.
A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.
Sci Transl Med
; 10(442)2018 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29794061
18.
Use of metadynamics in the design of isoDGR-based αvß3 antagonists to fine-tune the conformational ensemble.
Angew Chem Int Ed Engl
; 50(8): 1832-6, 2011 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21328650
19.
2D TR-NOESY experiments interrogate and rank ligand-receptor interactions in living human cancer cells.
Angew Chem Int Ed Engl
; 49(6): 1071-4, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20058288