Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases.

Provenzale, Isabella; Solari, Fiorella A; Schönichen, Claudia; Brouns, Sanne L N; Fernández, Delia I; Kuijpers, Marijke J E; van der Meijden, Paola E J; Gibbins, Jonathan M; Sickmann, Albert; Jones, Chris; Heemskerk, Johan W M.

FASEB J ; 38(4): e23468, 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-38334433

2.

Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets.

Bye, Alexander P; Hoepel, Willianne; Mitchell, Joanne L; Jégouic, Sophie; Loureiro, Silvia; Sage, Tanya; Vidarsson, Gestur; Nouta, Jan; Wuhrer, Manfred; de Taeye, Steven; van Gils, Marit; Kriek, Neline; Cooper, Nichola; Jones, Ian; den Dunnen, Jeroen; Gibbins, Jonathan M.

Blood ; 138(16): 1481-1489, 2021 10 21.

Artigo em Inglês | MEDLINE | ID: mdl-34315173

3.

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.

Sahli, Khaled A; Flora, Gagan D; Sasikumar, Parvathy; Maghrabi, Ali H; Holbrook, Lisa-Marie; AlOuda, Sarah K; Elgheznawy, Amro; Sage, Tanya; Stainer, Alexander R; Adiyaman, Recep; AboHassan, Mohammad; Crescente, Marilena; Kriek, Neline; Vaiyapuri, Sakthivel; Bye, Alexander P; Unsworth, Amanda J; Jones, Chris I; McGuffin, Liam J; Gibbins, Jonathan M.

Blood ; 137(6): 830-843, 2021 02 11.

Artigo em Inglês | MEDLINE | ID: mdl-32822477

4.

Multiple myeloma and its treatment contribute to increased platelet reactivity.

Mitchell, Joanne L; Khan, Dalia; Rana, Rekha H; Kriek, Neline; Unsworth, Amanda J; Sage, Tanya; Bye, Alexander P; Laffan, Michael; Shapiro, Susan; Thakurta, Anjan; Grech, Henri; Ramasamy, Karthik; Gibbins, Jonathan M.

Platelets ; 34(1): 2264940, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37822056

5.

Delineating Zinc Influx Mechanisms during Platelet Activation.

Kuravi, Sahithi J; Ahmed, Niaz S; Taylor, Kirk A; Capes, Emily M; Bye, Alex; Unsworth, Amanda J; Gibbins, Jonathan M; Pugh, Nicholas.

Int J Mol Sci ; 24(14)2023 Jul 20.

Artigo em Inglês | MEDLINE | ID: mdl-37511448

6.

Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan.

Provenzale, Isabella; De Simone, Ilaria; Gibbins, Jonathan M; Heemskerk, Johan W M; van der Meijden, Paola E J; Jones, Chris I.

Int J Mol Sci ; 24(17)2023 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-37686158

7.

The voltage-gated K⁺ channel Kv1.3 modulates platelet motility and α₂ß₁ integrin-dependent adhesion to collagen.

Wright, Joy R; Jones, Sarah; Parvathy, Sasikumar; Kaczmarek, Leonard K; Forsythe, Ian; Farndale, Richard W; Gibbins, Jonathan M; Mahaut-Smith, Martyn P.

Platelets ; 33(3): 451-461, 2022 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-34348571

8.

Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1.

De Simone, Ilaria; Baaten, Constance C F M J; Jandrot-Perrus, Martine; Gibbins, Jonathan M; Ten Cate, Hugo; Heemskerk, Johan W M; Jones, Chris I; van der Meijden, Paola E J.

Int J Mol Sci ; 23(18)2022 Sep 06.

Artigo em Inglês | MEDLINE | ID: mdl-36142125

9.

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.

Unsworth, Amanda J; Bye, Alexander P; Sage, Tanya; Gaspar, Renato S; Eaton, Nathan; Drew, Caleb; Stainer, Alexander; Kriek, Neline; Volberding, Peter J; Hutchinson, James L; Riley, Ryan; Jones, Sarah; Mundell, Stuart J; Cui, Weiguo; Falet, Hervé; Gibbins, Jonathan M.

Haematologica ; 106(7): 1968-1978, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-32467143

10.

Mind the gap: connexins and pannexins in platelet function.

Taylor, Kirk A; Little, Gemma; Gibbins, Jonathan M.

Platelets ; 32(7): 888-894, 2021 Oct 03.

Artigo em Inglês | MEDLINE | ID: mdl-33818243

11.

Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B.

Soriano Jerez, Eva M; Gibbins, Jonathan M; Hughes, Craig E.

Platelets ; 32(6): 761-769, 2021 Aug 18.

Artigo em Inglês | MEDLINE | ID: mdl-33646086

12.

Control of Platelet CLEC-2-Mediated Activation by Receptor Clustering and Tyrosine Kinase Signaling.

Martyanov, Alexey A; Balabin, Fedor A; Dunster, Joanne L; Panteleev, Mikhail A; Gibbins, Jonathan M; Sveshnikova, Anastasia N.

Biophys J ; 118(11): 2641-2655, 2020 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-32396849

13.

Functional redundancy between RAP1 isoforms in murine platelet production and function.

Stefanini, Lucia; Lee, Robert H; Paul, David S; O'Shaughnessy, Ellen C; Ghalloussi, Dorsaf; Jones, Christopher I; Boulaftali, Yacine; Poe, Kathryn O; Piatt, Raymond; Kechele, Dan O; Caron, Kathleen M; Hahn, Klaus M; Gibbins, Jonathan M; Bergmeier, Wolfgang.

Blood ; 132(18): 1951-1962, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30131434

14.

Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors.

Macwan, Ankit S; Boknäs, Niklas; Ntzouni, Maria P; Ramström, Sofia; Gibbins, Jonathan M; Faxälv, Lars; Lindahl, Tomas L.

Haematologica ; 104(7): 1482-1492, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30630981

15.

Flow cytometry for near-patient testing in premature neonates reveals variation in platelet function: a novel approach to guide platelet transfusion.

Waller, Amie K; Lantos, Lajos; Sammut, Audrienne; Salgin, Burak; McKinney, Harriet; Foster, Holly R; Kriek, Neline; Gibbins, Jonathan M; Stanworth, Simon J; Garner, Stephen F; Venkatesh, Vidheya; Curley, Anna; Belteki, Gusztav; Ghevaert, Cedric.

Pediatr Res ; 85(6): 874-884, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30742030

16.

Talin is a substrate for SUMOylation in migrating cancer cells.

Huang, Zhiyao; Barker, Diana; Gibbins, Jonathan M; Dash, Philip R.

Exp Cell Res ; 370(2): 417-425, 2018 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-30003879

17.

Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.

Unsworth, Amanda J; Bye, Alexander P; Kriek, Neline; Sage, Tanya; Osborne, Ashley A; Donaghy, Dillon; Gibbins, Jonathan M.

Platelets ; 30(6): 762-772, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30252580

18.

Evidence for shear-mediated Ca²⁺ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line.

Ilkan, Zeki; Wright, Joy R; Goodall, Alison H; Gibbins, Jonathan M; Jones, Chris I; Mahaut-Smith, Martyn P.

J Biol Chem ; 292(22): 9204-9217, 2017 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-28416610

19.

Platelets stop us leaking.

Gibbins, Jonathan M.

Blood ; 127(12): 1528-9, 2016 Mar 24.

Artigo em Inglês | MEDLINE | ID: mdl-27013214

20.

Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib.

Bye, Alexander P; Kriek, Neline; Sage, Tanya; Rawlings, Suzannah J; Prodger, Catherine; Kesavan, Murali; Lees, Charlotte; Booth, Stephen; Cowen, Louise G; Shefferd, Kirsty; Desborough, Michael J; Gibbins, Jonathan M; Eyre, Toby A.

Haematologica ; 108(5): 1429-1435, 2023 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-36519322

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