Detalhe da pesquisa
1.
Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signaling.
J Biol Chem
; 299(9): 105107, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517699
2.
Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR.
J Biol Chem
; 298(7): 102104, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35679899
3.
Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.
PLoS Pathog
; 17(1): e1009275, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513206
4.
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Mol Ther
; 30(9): 2998-3016, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526097
5.
A Non-Canonical Function of Gß as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.
Mol Cell
; 58(5): 794-803, 2015 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982117
6.
Structure-based discovery of opioid analgesics with reduced side effects.
Nature
; 537(7619): 185-190, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27533032
7.
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.
Immunity
; 36(6): 933-46, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749352
8.
Molecular control of δ-opioid receptor signalling.
Nature
; 506(7487): 191-6, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24413399
9.
Propagation of the Allosteric Modulation Induced by Sodium in the δ-Opioid Receptor.
Chemistry
; 23(19): 4615-4624, 2017 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28182309
10.
G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.
J Biol Chem
; 289(48): 33245-57, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25271165
11.
Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist.
Tetrahedron Lett
; 56(23): 3420-3422, 2015 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26120215
12.
Heterotrimeric G-protein signaling is critical to pathogenic processes in Entamoeba histolytica.
PLoS Pathog
; 8(11): e1003040, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23166501
13.
Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.
Pharmacol Rev
; 63(3): 728-49, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737532
14.
G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gß and Gαi protein subunits.
J Biol Chem
; 287(7): 4863-74, 2012 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22167191
15.
Regulation of the subcellular localization of the G-protein subunit regulator GPSM3 through direct association with 14-3-3 protein.
J Biol Chem
; 287(37): 31270-9, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22843681
16.
Profiling of basal and ligand-dependent GPCR activities by means of a polyvalent cell-based high-throughput platform.
Nat Commun
; 14(1): 3684, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37407564
17.
Functional Characterization of Sodium Channel Inhibitors at the Delta-Opioid Receptor.
ACS Omega
; 7(20): 16939-16951, 2022 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647460
18.
Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
FEBS Lett
; 596(7): 898-909, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122247
19.
Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron.
iScience
; 25(11): 105316, 2022 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36254158
20.
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models.
Commun Biol
; 5(1): 933, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36085335