Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Extended-Synaptotagmin-1 and -2 control T cell signaling and function.

Benavides, Nathalia; Giraudo, Claudio G.

EMBO Rep ; 25(1): 286-303, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38177911

2.

Novel Compound Heterozygous ZAP70 R37G A507T Mutations in Infant with Severe Immunodeficiency.

Benavides, Nathalia; White, Jason C; Sanmillan, Maria L; Thomas, Morgan; Le, Trong; Caywood, Emi; Giraudo, Claudio G.

J Clin Immunol ; 44(1): 27, 2023 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-38129328

3.

SM protein Munc18-2 facilitates transition of Syntaxin 11-mediated lipid mixing to complete fusion for T-lymphocyte cytotoxicity.

Spessott, Waldo A; Sanmillan, Maria L; McCormick, Margaret E; Kulkarni, Vineet V; Giraudo, Claudio G.

Proc Natl Acad Sci U S A ; 114(11): E2176-E2185, 2017 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-28265073

4.

Syntaxin 4 mediates endosome recycling for lytic granule exocytosis in cytotoxic T-lymphocytes.

Spessott, Waldo A; Sanmillan, Maria L; Kulkarni, Vineet V; McCormick, Margaret E; Giraudo, Claudio G.

Traffic ; 18(7): 442-452, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28471021

5.

RHOG: Rac1-ing up another HLH gene.

Nichols, Kim E; Giraudo, Claudio G.

Blood ; 137(15): 1990-1991, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33856445

6.

Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion.

Spessott, Waldo A; Sanmillan, Maria L; McCormick, Margaret E; Patel, Nishant; Villanueva, Joyce; Zhang, Kejian; Nichols, Kim E; Giraudo, Claudio G.

Blood ; 125(10): 1566-77, 2015 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-25564401

7.

Identification of a site in Sar1 involved in the interaction with the cytoplasmic tail of glycolipid glycosyltransferases.

Quintero, Cristián A; Giraudo, Claudio G; Villarreal, Marcos; Montich, Guillermo; Maccioni, Hugo J F.

J Biol Chem ; 285(39): 30340-6, 2010 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-20650895

8.

Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation.

Ouahed, Jodie; Kelsen, Judith R; Spessott, Waldo A; Kooshesh, Kameron; Sanmillan, Maria L; Dawany, Noor; Sullivan, Kathleen E; Hamilton, Kathryn E; Slowik, Voytek; Nejentsev, Sergey; Neves, João Farela; Flores, Helena; Chung, Wendy K; Wilson, Ashley; Anyane-Yeboa, Kwame; Wou, Karen; Jain, Preti; Field, Michael; Tollefson, Sophia; Dent, Maiah H; Li, Dalin; Naito, Takeo; McGovern, Dermot P B; Kwong, Andrew C; Taliaferro, Faith; Ordovas-Montanes, Jose; Horwitz, Bruce H; Kotlarz, Daniel; Klein, Christoph; Evans, Jonathan; Dorsey, Jill; Warner, Neil; Elkadri, Abdul; Muise, Aleixo M; Goldsmith, Jeffrey; Thompson, Benjamin; Engelhardt, Karin R; Cant, Andrew J; Hambleton, Sophie; Barclay, Andrew; Toth-Petroczy, Agnes; Vuzman, Dana; Carmichael, Nikkola; Bodea, Corneliu; Cassa, Christopher A; Devoto, Marcella; Maas, Richard L; Behrens, Edward M; Giraudo, Claudio G; Snapper, Scott B.

J Crohns Colitis ; 15(11): 1908-1919, 2021 Nov 08.

Artigo em Inglês | MEDLINE | ID: mdl-33891011

9.

SNAREs can promote complete fusion and hemifusion as alternative outcomes.

Giraudo, Claudio G; Hu, Chuan; You, Daoqi; Slovic, Avram M; Mosharov, Eugene V; Sulzer, David; Melia, Thomas J; Rothman, James E.

J Cell Biol ; 170(2): 249-60, 2005 Jul 18.

Artigo em Inglês | MEDLINE | ID: mdl-16027221

10.

STXBP2-R190C Variant in a Patient With Neonatal Hemophagocytic Lymphohistiocytosis (HLH) and G6PD Deficiency Reveals a Critical Role of STXBP2 Domain 2 on Granule Exocytosis.

Benavides, Nathalia; Spessott, Waldo A; Sanmillan, Maria L; Vargas, Marcelo; Livingston, Mylynda S; Erickson, Nissa; Pozos, Tamara C; McCormick, Margaret E; Scharrig, Emilia; Messinger, Yoav H; Giraudo, Claudio G.

Front Immunol ; 11: 545414, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-33162974

11.

Endoplasmic reticulum export of glycosyltransferases depends on interaction of a cytoplasmic dibasic motif with Sar1.

Giraudo, Claudio G; Maccioni, Hugo J F.

Mol Biol Cell ; 14(9): 3753-66, 2003 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-12972562

12.

Ganglioside glycosyltransferases and newly synthesized gangliosides are excluded from detergent-insoluble complexes of Golgi membranes.

Crespo, Pilar M; Zurita, Adolfo R; Giraudo, Claudio G; Maccioni, Hugo J F; Daniotti, Jose L.

Biochem J ; 377(Pt 3): 561-8, 2004 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-14565845

13.

Endogenous species of mammalian nonmuscle myosin IIA and IIB include activated monomers and heteropolymers.

Shutova, Maria S; Spessott, Waldo A; Giraudo, Claudio G; Svitkina, Tatyana.

Curr Biol ; 24(17): 1958-68, 2014 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-25131674

14.

Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex.

Shi, Lei; Kümmel, Daniel; Coleman, Jeff; Melia, Thomas J; Giraudo, Claudio G.

Mol Biol Cell ; 22(21): 4150-60, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21900493

15.

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state.

Li, Feng; Pincet, Frédéric; Perez, Eric; Giraudo, Claudio G; Tareste, David; Rothman, James E.

Nat Struct Mol Biol ; 18(8): 941-6, 2011 Jul 24.

Artigo em Inglês | MEDLINE | ID: mdl-21785413

16.

Complexin cross-links prefusion SNAREs into a zigzag array.

Kümmel, Daniel; Krishnakumar, Shyam S; Radoff, Daniel T; Li, Feng; Giraudo, Claudio G; Pincet, Frederic; Rothman, James E; Reinisch, Karin M.

Nat Struct Mol Biol ; 18(8): 927-33, 2011 Jul 24.

Artigo em Inglês | MEDLINE | ID: mdl-21785414

17.

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion.

Krishnakumar, Shyam S; Radoff, Daniel T; Kümmel, Daniel; Giraudo, Claudio G; Li, Feng; Khandan, Lavan; Baguley, Stephanie Wood; Coleman, Jeff; Reinisch, Karin M; Pincet, Frederic; Rothman, James E.

Nat Struct Mol Biol ; 18(8): 934-40, 2011 Jul 24.

Artigo em Inglês | MEDLINE | ID: mdl-21785412

18.

Alternative zippering as an on-off switch for SNARE-mediated fusion.

Giraudo, Claudio G; Garcia-Diaz, Alejandro; Eng, William S; Chen, Yuhang; Hendrickson, Wayne A; Melia, Thomas J; Rothman, James E.

Science ; 323(5913): 512-6, 2009 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-19164750

19.

Distinct domains of complexins bind SNARE complexes and clamp fusion in vitro.

Giraudo, Claudio G; Garcia-Diaz, Alejandro; Eng, William S; Yamamoto, Ai; Melia, Thomas J; Rothman, James E.

J Biol Chem ; 283(30): 21211-9, 2008 Jul 25.

Artigo em Inglês | MEDLINE | ID: mdl-18499660

20.

Cytoplasmic tails of SialT2 and GalNAcT impose their respective proximal and distal Golgi localization.

Uliana, Andrea S; Giraudo, Claudio G; Maccioni, Hugo J F.

Traffic ; 7(5): 604-12, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16643282

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