Detalhe da pesquisa
1.
Antinociceptive Effect of Dillenia indica (Linn.) Mediated by Opioid and Cannabinoid Systems: Pharmacological and Chemical Studies.
Chem Biodivers
; 21(3): e202301508, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092696
2.
In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models.
Molecules
; 27(23)2022 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500726
3.
In vivo evaluation of anti-Leishmania activity of alkyltriazoles and alkylphosphocholines by oral route.
Exp Parasitol
; 226-227: 108123, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34144040
4.
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
Molecules
; 25(14)2020 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32664425
5.
Synthesis and evaluation of the antileishmanial activity of silver compounds containing imidazolidine-2-thione.
J Biol Inorg Chem
; 24(3): 419-432, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30949838
6.
Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor.
J Enzyme Inhib Med Chem
; 28(4): 661-70, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22468751
7.
Curcumin, Resveratrol and Cannabidiol as Natural Key Prototypes in Drug Design for Neuroprotective Agents.
Curr Neuropharmacol
; 20(7): 1297-1328, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825873
8.
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
RSC Med Chem
; 13(5): 568-584, 2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35694691
9.
Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development and Promising Results Obtained from Multi-target Approaches.
Curr Drug Targets
; 22(5): 505-538, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814524
10.
Semysinthetic biflavonoid Morelloflavone-7,4',7â³,3â´,4â´-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 and Furin.
Biochim Biophys Acta Gen Subj
; 1865(12): 130016, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34560176
11.
Molecular Hybridization as a Tool in the Design of Multi-target Directed Drug Candidates for Neurodegenerative Diseases.
Curr Neuropharmacol
; 18(5): 348-407, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31631821
12.
Multi-Target Directed Drugs as a Modern Approach for Drug Design Towards Alzheimer's Disease: An Update.
Curr Med Chem
; 25(29): 3491-3525, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29332563
13.
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Eur J Med Chem
; 147: 48-65, 2018 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29421570
14.
Biological and Chemical Aspects of Natural Biflavonoids from Plants: A Brief Review.
Mini Rev Med Chem
; 17(10): 834-862, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27823559
15.
Leishmanicidal, antiproteolytic, and mutagenic evaluation of alkyltriazoles and alkylphosphocholines.
Eur J Med Chem
; 101: 24-33, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26112378
16.
Analgesic and anti-inflammatory activities of the 2,8-dihydroxy-1,6-dimethoxyxanthone from Haploclathra paniculata (Mart) Benth (Guttiferae).
J Med Food
; 17(6): 686-93, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476225
17.
Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp.
Food Chem
; 132(3): 1230-1235, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29243605
18.
Leishmanicidal, antiproteolytic and antioxidant evaluation of natural biflavonoids isolated from Garcinia brasiliensis and their semisynthetic derivatives.
Eur J Med Chem
; 58: 613-23, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23178961