Detalhe da pesquisa
1.
The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis.
Cell
; 138(2): 377-88, 2009 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19632185
2.
Divergent synthesis of fractionated Cannabis sativa extract led to multiple cannabinoids C-&O-glycosides with anti-proliferative/anti-metastatic properties.
Bioorg Chem
; 143: 107030, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091718
3.
Identification of new modulator of DNA repairing pathways based on natural product (±)-peharmaline A.
Bioorg Med Chem
; 91: 117365, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37392722
4.
Diversity, Antimicrobial, Antioxidant, and Anticancer Activity of Culturable Fungal Endophyte Communities in Cordia dichotoma.
Molecules
; 28(19)2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37836769
5.
Heterochiral dipeptide d-phenylalanyl- l-phenylalanine (H-D Phe-L Phe-OH) as a potential inducer of metastatic suppressor NM23H1 in p53 wild-type and mutant cells.
Mol Carcinog
; 61(12): 1143-1160, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239557
6.
Palladium catalyzed migratory heck coupling of arteannuin B and boronic acids: An approach towards the synthesis of antiproliferative agents in breast and lung cancer cells.
Bioorg Chem
; 122: 105694, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286922
7.
Integration of EMT and cellular survival instincts in reprogramming of programmed cell death to anastasis.
Cancer Metastasis Rev
; 39(2): 553-566, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32020420
8.
Par-4 activation restrains EMT-induced chemoresistance in PDAC by attenuating MDM-2.
Pancreatology
; 20(8): 1698-1710, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33039292
9.
Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78.
Breast Cancer Res Treat
; 177(2): 307-323, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175498
10.
Dual role of Par-4 in abrogation of EMT and switching on Mesenchymal to Epithelial Transition (MET) in metastatic pancreatic cancer cells.
Mol Carcinog
; 57(9): 1102-1115, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29672923
11.
Cyclodipeptide c(Orn-Pro) Conjugate with 4-Ethylpiperic Acid Abrogates Cancer Cell Metastasis through Modulating MDM2.
Bioconjug Chem
; 29(1): 164-175, 2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29216716
12.
Par-4 dependent modulation of cellular ß-catenin by medicinal plant natural product derivative 3-azido Withaferin A.
Mol Carcinog
; 55(5): 864-81, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25969134
13.
Hemisynthesis and cytotoxic evaluation of manoyl oxide analogs from sclareol: effect of two tertiary hydroxyls & Heck coupling on cytotoxicity.
Nat Prod Res
; : 1-10, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38635350
14.
Canonical DDR activation by EMT inducing agent 5-Fluorouracil is modulated by a cannabinoid based combinatorial approach via inducing autophagy and suppression of vimentin expression.
Biochem Pharmacol
; 223: 116126, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490521
15.
Synthesis and characterization of piperic acid conjugates with homochiral and heterochiral dipeptides containing phenylalanine and their application in skin cancer.
Peptides
; 170: 171113, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923167
16.
Glabridin plays dual action to intensify anti-metastatic potential of paclitaxel via impeding CYP2C8 in liver and CYP2J2/EETs in tumor of an orthotopic mouse model of breast cancer.
Chem Biol Interact
; 382: 110605, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37419298
17.
Quinoxalinone substituted pyrrolizine (4h)-induced dual inhibition of AKT and ERK instigates apoptosis in breast and colorectal cancer by modulating mitochondrial membrane potential.
Eur J Pharmacol
; 957: 175945, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37541376
18.
Rottlerin renders a selective and highly potent CYP2C8 inhibition to impede EET formation for implication in cancer therapy.
Chem Biol Interact
; 380: 110524, 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146929
19.
Synthesis, conformation and cytotoxic activity of short hybrid peptides containing conformationally constrained 1-(aminomethyl)cyclohexanecarboxylic acid and gabapentin.
Peptides
; 158: 170897, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279986
20.
Rottlerin promotes anti-metastatic events by ameliorating pharmacological parameters of paclitaxel: An in-vivo investigation in the orthotopic mouse model of breast cancer.
Chem Biol Interact
; 366: 110109, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35995259