Detalhe da pesquisa
1.
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Mol Psychiatry
; 26(10): 5766-5788, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647257
2.
Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Mol Psychiatry
; 26(10): 5789, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34272490
3.
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels.
EBioMedicine
; 94: 104692, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451904
4.
Modeling Down syndrome in cells: From stem cells to organoids.
Prog Brain Res
; 251: 55-90, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32057312