Detalhe da pesquisa
1.
Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin.
Proc Natl Acad Sci U S A
; 119(19): e2200102119, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35500114
2.
Intermolecular latency regulates the essential C-terminal signal peptidase and sortase of the Porphyromonas gingivalis type-IX secretion system.
Proc Natl Acad Sci U S A
; 118(40)2021 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34593635
3.
Multiple Architectures and Mechanisms of Latency in Metallopeptidase Zymogens.
Chem Rev
; 118(11): 5581-5597, 2018 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29775286
4.
Reply to Harwood et al.: Alternative functional conformations of native human α2-macroglobulin.
Proc Natl Acad Sci U S A
; 119(37): e2211048119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972982
5.
Matrix metalloproteinases outside vertebrates.
Biochim Biophys Acta Mol Cell Res
; 1864(11 Pt A): 2026-2035, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28392403
6.
A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome.
J Biol Chem
; 292(26): 10883-10898, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512127
7.
Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome.
J Biol Chem
; 292(14): 5724-5735, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28196869
8.
LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.
Nat Methods
; 12(1): 55-8, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25419962
9.
α2-Macroglobulins: Structure and Function.
Subcell Biochem
; 83: 149-183, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28271476
10.
Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition.
Proc Natl Acad Sci U S A
; 112(27): 8290-5, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100869
11.
Structural and functional insight into pan-endopeptidase inhibition by α2-macroglobulins.
Biol Chem
; 398(9): 975-994, 2017 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28253193
12.
Combining phase information in reciprocal space for molecular replacement with partial models.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 9): 1931-45, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26327383
13.
Expression and purification of integral membrane metallopeptidase HtpX.
Protein Expr Purif
; 99: 113-8, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24769134
14.
Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog.
Proc Natl Acad Sci U S A
; 108(5): 1856-61, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21233422
15.
Structural and functional insights into the C-terminal signal domain of the Bacteroidetes type-IX secretion system.
Open Biol
; 14(6): 230448, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38862016
16.
Frozen fresh blood plasma preserves the functionality of native human α2-macroglobulin.
Sci Rep
; 13(1): 4579, 2023 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36941303
17.
A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.
Chem Sci
; 14(4): 869-888, 2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36755705
18.
The crystal structure of human α2-macroglobulin reveals a unique molecular cage.
Angew Chem Int Ed Engl
; 51(14): 3340-4, 2012 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22290936
19.
An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution.
J Mol Biol
; 433(13): 166954, 2021 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771572
20.
Analysis of the inhibiting activity of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) on matrix metalloproteinases.
Sci Rep
; 10(1): 6317, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32286475