Detalhe da pesquisa
1.
Mapping an Adeno-associated Virus 9-Specific Neutralizing Epitope To Develop Next-Generation Gene Delivery Vectors.
J Virol
; 92(20)2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30089698
2.
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function.
Mol Ther
; 26(12): 2848-2862, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30343890
3.
Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.
Mol Ther
; 22(11): 1900-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25048217
4.
Structural insights into adeno-associated virus serotype 5.
J Virol
; 87(20): 11187-99, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23926356
5.
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
J Virol
; 87(9): 5128-40, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23449783
6.
Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector.
Mol Ther
; 20(2): 443-55, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22068425
7.
Characterization of novel canine bocaviruses and their association with respiratory disease.
J Gen Virol
; 93(Pt 2): 341-346, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031527
8.
Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH.
Microbiology (Reading)
; 158(Pt 5): 1350-1358, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343352
9.
Production, purification, crystallization and structure determination of H-1 Parvovirus.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 12): 1571-6, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23192051
10.
Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.
Mol Ther
; 19(6): 1070-8, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21364538
11.
Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.
Mol Ther
; 19(2): 293-301, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21045809
12.
Structure-function correlation of G6, a novel small molecule inhibitor of Jak2: indispensability of the stilbenoid core.
J Biol Chem
; 285(41): 31399-407, 2010 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20667821
13.
Structural characterization of the dual glycan binding adeno-associated virus serotype 6.
J Virol
; 84(24): 12945-57, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20861247
14.
Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.
Proc Natl Acad Sci U S A
; 105(22): 7827-32, 2008 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18511559
15.
Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.
Biochemistry
; 48(6): 1322-31, 2009 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19170619
16.
Heparin binding induces conformational changes in Adeno-associated virus serotype 2.
J Struct Biol
; 165(3): 146-56, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19121398
17.
Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942).
J Virol
; 82(17): 8911-6, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18524816
18.
Surface loop dynamics in adeno-associated virus capsid assembly.
J Virol
; 82(11): 5178-89, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18367523
19.
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr D Biol Crystallogr
; 64(Pt 11): 1172-8, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19020356
20.
Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
J Med Chem
; 51(4): 852-60, 2008 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18215016