Detalhe da pesquisa
1.
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Nature
; 593(7860): 597-601, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33902106
2.
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Cell Genom
; 3(12): 100426, 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116120
3.
The roles of ATF2 (activating transcription factor 2) in tumorigenesis.
Biochem Soc Trans
; 40(1): 230-4, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22260696
4.
Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.
Sci Adv
; 8(31): eabn4886, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921412
5.
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.
Leukemia
; 35(4): 1012-1022, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764680
6.
SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.
Blood Adv
; 5(9): 2412-2425, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33956058
7.
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.
Nat Genet
; 53(10): 1443-1455, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34556857
8.
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
J Exp Med
; 216(4): 966-981, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890554
9.
Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.
Leukemia
; 37(10): 2133-2137, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37464070
10.
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Nat Genet
; 50(6): 883-894, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29736013
11.
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
Nat Commun
; 9(1): 5378, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30568163
12.
Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Nat Genet
; 54(7): 1062, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35701672
13.
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Cell Rep
; 17(4): 1193-1205, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760321
14.
JNK suppresses tumor formation via a gene-expression program mediated by ATF2.
Cell Rep
; 9(4): 1361-74, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25456131
15.
Heme oxygenase-1 accelerates cutaneous wound healing in mice.
PLoS One
; 4(6): e5803, 2009 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19495412