Detalhe da pesquisa
1.
CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1.
J Biol Chem
; 294(10): 3744-3759, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635404
2.
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.
Proc Natl Acad Sci U S A
; 111(9): 3620-5, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550511
3.
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways.
Cell Mol Neurobiol
; 36(3): 377-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908139
4.
From molecule to molecule and cell to cell: prion-like mechanisms in amyotrophic lateral sclerosis.
Neurobiol Dis
; 77: 257-65, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25701498
5.
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
Proc Natl Acad Sci U S A
; 108(39): 16398-403, 2011 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930926
6.
Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit.
J Toxicol Environ Health A
; 74(22-24): 1433-59, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22043906
7.
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites.
J Cell Biol
; 217(10): 3593-3607, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018089
8.
Riboflavin enhances the assembly of mitochondrial cytochrome c oxidase in C. elegans NADH-ubiquinone oxidoreductase mutants.
Biochim Biophys Acta
; 1757(2): 115-22, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16443191
9.
Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegans.
Methods Mol Biol
; 372: 51-66, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18314717
10.
Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture.
Methods Mol Biol
; 1658: 357-367, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28861801
11.
Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS).
Cold Spring Harb Perspect Med
; 7(8)2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003278
12.
TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion.
Sci Rep
; 6: 22155, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26926802
13.
Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis.
Prion
; 8(1): 33-41, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24394345
14.
Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding.
Prion
; 8(5): 331-5, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25551548
15.
Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
PLoS One
; 7(4): e35050, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22493728
16.
Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans.
Proc Natl Acad Sci U S A
; 102(51): 18367-72, 2005 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16344465
17.
Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis.
Hum Mol Genet
; 13(3): 303-14, 2004 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14662656