Detalhe da pesquisa
1.
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.
Nat Immunol
; 16(10): 1025-33, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26343537
2.
Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.
EMBO J
; 41(17): e111608, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35833542
3.
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Nat Immunol
; 13(3): 223-228, 2012 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22327569
4.
Nsp16 shields SARS-CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction.
EMBO Rep
; 23(12): e55648, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36285486
5.
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.
J Biol Chem
; 298(6): 102004, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504352
6.
Human TRIM5α senses and restricts LINE-1 elements.
Proc Natl Acad Sci U S A
; 117(30): 17965-17976, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32651277
7.
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
PLoS Pathog
; 16(8): e1008752, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32760121
8.
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
Retrovirology
; 12: 103, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26667483
9.
Restriction of diverse retroviruses by SAMHD1.
Retrovirology
; 10: 26, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23497255
10.
A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements.
Front Immunol
; 14: 1168589, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37180175
11.
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
J Exp Med
; 220(1)2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346347
12.
Evidence for an activation domain at the amino terminus of simian immunodeficiency virus Vpx.
J Virol
; 84(3): 1387-96, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19923175
13.
SAMHD1 and Viral Ways around It.
Viruses
; 13(3)2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33801276
14.
Recognize Yourself-Innate Sensing of Non-LTR Retrotransposons.
Viruses
; 13(1)2021 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33445593
15.
Accessories to the crime: recent advances in HIV accessory protein biology.
Curr HIV/AIDS Rep
; 6(1): 36-42, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19149995
16.
Human cytomegalovirus overcomes SAMHD1 restriction in macrophages via pUL97.
Nat Microbiol
; 4(12): 2260-2272, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548682
17.
A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.
Nat Microbiol
; 4(12): 2273-2284, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548683
18.
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.
Cell Host Microbe
; 25(6): 858-872.e13, 2019 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175045
19.
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Mob DNA
; 9: 11, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610582
20.
SAMHD1 in Retroviral Restriction and Innate Immune Sensing--Should We Leash the Hound?
Curr HIV Res
; 14(3): 225-34, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26957197