Detalhe da pesquisa
1.
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses.
Immunity
; 55(3): 512-526.e9, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263569
2.
Peripheral T cell expansion predicts tumour infiltration and clinical response.
Nature
; 579(7798): 274-278, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32103181
3.
CD96 functions as a co-stimulatory receptor to enhance CD8+ T cell activation and effector responses.
Eur J Immunol
; 50(6): 891-902, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32043568
4.
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells.
Nat Immunol
; 10(1): 66-74, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19029905
5.
The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Nat Immunol
; 10(1): 48-57, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19011627
6.
A Platform for Extracellular Interactome Discovery Identifies Novel Functional Binding Partners for the Immune Receptors B7-H3/CD276 and PVR/CD155.
Mol Cell Proteomics
; 18(11): 2310-2323, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308249
7.
CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1.
Proc Natl Acad Sci U S A
; 115(50): E11731-E11740, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504141
8.
TIGIT: A Key Inhibitor of the Cancer Immunity Cycle.
Trends Immunol
; 38(1): 20-28, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27793572
9.
TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic Disease.
J Immunol
; 196(9): 3570-80, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27016609
10.
Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
J Biol Chem
; 291(25): 13014-27, 2016 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27056325
11.
Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.
J Biol Chem
; 290(50): 29732-41, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491012
12.
Dimerization of LTßR by LTα1ß2 is necessary and sufficient for signal transduction.
Proc Natl Acad Sci U S A
; 110(49): 19896-901, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24248355
13.
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc Natl Acad Sci U S A
; 109(14): 5399-404, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421438
14.
HPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics.
Nat Commun
; 15(1): 3725, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697971
15.
Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun
; 15(1): 2625, 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38521763
16.
A role for Th17 cells in the regulation of tertiary lymphoid follicles.
Eur J Immunol
; 42(9): 2255-62, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22949324
17.
Immune complex-mediated cell activation from systemic lupus erythematosus and rheumatoid arthritis patients elaborate different requirements for IRAK1/4 kinase activity across human cell types.
J Immunol
; 186(2): 1279-88, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21160042
18.
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer.
Cancer Cell
; 40(3): 289-300.e4, 2022 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216676
19.
Resurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-α antibody.
Proteomics
; 11(3): 395-405, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21268269
20.
Lymphotoxin-alphabeta heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.
Cytokine
; 51(1): 78-86, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20356761