Detalhe da pesquisa
1.
SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops.
Mol Cell
; 83(20): 3593-3595, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863028
2.
What repeat expansion disorders can teach us about the Central Dogma.
Mol Cell
; 83(3): 324-329, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736306
3.
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops.
Nucleic Acids Res
; 51(21): 11584-11599, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37843099
4.
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination.
Mol Cell
; 42(6): 794-805, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21700224
5.
Out of balance: R-loops in human disease.
PLoS Genet
; 10(9): e1004630, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25233079
6.
R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.
PLoS Genet
; 10(5): e1004318, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24787137
7.
Mechanisms of transcriptional dysregulation in repeat expansion disorders.
Biochem Soc Trans
; 42(4): 1123-8, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25110013
8.
Primary microRNA transcripts are processed co-transcriptionally.
Nat Struct Mol Biol
; 15(9): 902-9, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19172742
9.
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.
Nat Genet
; 55(10): 1721-1734, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735199
10.
Intronic microRNAs: a crossroad in gene regulation.
Biochem Soc Trans
; 40(4): 759-61, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817729
11.
R-Loop Immunoprecipitation: A Method to Detect R-Loop Interacting Factors.
Methods Mol Biol
; 2528: 215-237, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35704194
12.
RNase H2, mutated in Aicardi-Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation.
Nat Commun
; 13(1): 2961, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618715
13.
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes.
J Exp Med
; 219(4)2022 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262626
14.
Hypoxia-induced SETX links replication stress with the unfolded protein response.
Nat Commun
; 12(1): 3686, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140498
15.
Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.
RNA
; 14(2): 359-66, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18065715
16.
Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.
Nature
; 432(7016): 522-5, 2004 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15565158
17.
Transcription-dependent DNA double-strand breaks and human disease.
Mol Cell Oncol
; 7(2): 1691905, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32158914
18.
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
Nat Genet
; 52(1): 48-55, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31844323
19.
Pause sites promote transcriptional termination of mammalian RNA polymerase II.
Mol Cell Biol
; 26(10): 3986-96, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16648491
20.
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks.
Cell Rep
; 28(12): 3167-3181.e6, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533039