Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.

Allou, Lila; Balzano, Sara; Magg, Andreas; Quinodoz, Mathieu; Royer-Bertrand, Beryl; Schöpflin, Robert; Chan, Wing-Lee; Speck-Martins, Carlos E; Carvalho, Daniel Rocha; Farage, Luciano; Lourenço, Charles Marques; Albuquerque, Regina; Rajagopal, Srilakshmi; Nampoothiri, Sheela; Campos-Xavier, Belinda; Chiesa, Carole; Niel-Bütschi, Florence; Wittler, Lars; Timmermann, Bernd; Spielmann, Malte; Robson, Michael I; Ringel, Alessa; Heinrich, Verena; Cova, Giulia; Andrey, Guillaume; Prada-Medina, Cesar A; Pescini-Gobert, Rosanna; Unger, Sheila; Bonafé, Luisa; Grote, Phillip; Rivolta, Carlo; Mundlos, Stefan; Superti-Furga, Andrea.

Nature ; 592(7852): 93-98, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33568816

2.

Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development via its RNA:dsDNA triplex element.

Ali, Tamer; Rogala, Sandra; Krause, Nina M; Bains, Jasleen Kaur; Melissari, Maria-Theodora; Währisch, Sandra; Schwalbe, Harald; Herrmann, Bernhard G; Grote, Phillip.

Nucleic Acids Res ; 51(12): 6227-6237, 2023 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-37207329

3.

Biophysical Investigation of RNA â DNA : DNA Triple Helix and RNA : DNA Heteroduplex Formation by the lncRNAs MEG3 and Fendrr.

Krause, Nina M; Bains, Jasleen K; Blechar, Julius; Richter, Christian; Bessi, Irene; Grote, Phillip; Leisegang, Matthias S; Brandes, Ralf P; Schwalbe, Harald.

Chembiochem ; 25(10): e202400049, 2024 May 17.

Artigo em Inglês | MEDLINE | ID: mdl-38456652

4.

Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses.

Heumüller, Andreas W; Jones, Alisha N; Mourão, André; Klangwart, Marius; Shi, Chenyue; Wittig, Ilka; Fischer, Ariane; Muhly-Reinholz, Marion; Buchmann, Giulia K; Dieterich, Christoph; Potente, Michael; Braun, Thomas; Grote, Phillip; Jaé, Nicolas; Sattler, Michael; Dimmeler, Stefanie.

Circ Res ; 130(1): 67-79, 2022 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-34789007

5.

X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems.

Kolvenbach, Caroline M; Felger, Tim; Schierbaum, Luca; Thiffault, Isabelle; Pastinen, Tomi; Szczepanska, Maria; Zaniew, Marcin; Adamczyk, Piotr; Bayat, Allan; Yilmaz, Öznur; Lindenberg, Tobias T; Thiele, Holger; Hildebrandt, Friedhelm; Hinderhofer, Katrin; Moog, Ute; Hilger, Alina C; Sullivan, Bonnie; Bartik, Lauren; Gnys, Piotr; Grote, Phillip; Odermatt, Benjamin; Reutter, Heiko M; Dworschak, Gabriel C.

J Med Genet ; 60(6): 587-596, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36379543

6.

Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction.

Kolvenbach, Caroline M; Dworschak, Gabriel C; Frese, Sandra; Japp, Anna S; Schuster, Peggy; Wenzlitschke, Nina; Yilmaz, Öznur; Lopes, Filipa M; Pryalukhin, Alexey; Schierbaum, Luca; van der Zanden, Loes F M; Kause, Franziska; Schneider, Ronen; Taranta-Janusz, Katarzyna; Szczepanska, Maria; Pawlaczyk, Krzysztof; Newman, William G; Beaman, Glenda M; Stuart, Helen M; Cervellione, Raimondo M; Feitz, Wouter F J; van Rooij, Iris A L M; Schreuder, Michiel F; Steffens, Martijn; Weber, Stefanie; Merz, Waltraut M; Feldkötter, Markus; Hoppe, Bernd; Thiele, Holger; Altmüller, Janine; Berg, Christoph; Kristiansen, Glen; Ludwig, Michael; Reutter, Heiko; Woolf, Adrian S; Hildebrandt, Friedhelm; Grote, Phillip; Zaniew, Marcin; Odermatt, Benjamin; Hilger, Alina C.

Am J Hum Genet ; 104(5): 994-1006, 2019 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-31051115

7.

Inhibition of the Hypoxia-Inducible Factor 1α-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease.

Mirtschink, Peter; Bischof, Corinne; Pham, Minh-Duc; Sharma, Rahul; Khadayate, Sanjay; Rossi, Geetha; Fankhauser, Niklaus; Traub, Shuyang; Sossalla, Samuel; Hagag, Eman; Berthonneche, Corinne; Sarre, Alexandre; Stehr, Sebastian N; Grote, Phillip; Pedrazzini, Thierry; Dimmeler, Stefanie; Krek, Wilhelm; Krishnan, Jaya.

Circulation ; 139(24): 2778-2792, 2019 06 11.

Artigo em Inglês | MEDLINE | ID: mdl-30922078

8.

BRACHYURY directs histone acetylation to target loci during mesoderm development.

Beisaw, Arica; Tsaytler, Pavel; Koch, Frederic; Schmitz, Sandra U; Melissari, Maria-Theodora; Senft, Anna D; Wittler, Lars; Pennimpede, Tracie; Macura, Karol; Herrmann, Bernhard G; Grote, Phillip.

EMBO Rep ; 19(1): 118-134, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29141987

9.

Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes.

Bischoff, Florian C; Werner, Astrid; John, David; Boeckel, Jes-Niels; Melissari, Maria-Theodora; Grote, Phillip; Glaser, Simone F; Demolli, Shemsi; Uchida, Shizuka; Michalik, Katharina M; Meder, Benjamin; Katus, Hugo A; Haas, Jan; Chen, Wei; Pullamsetti, Soni S; Seeger, Werner; Zeiher, Andreas M; Dimmeler, Stefanie; Zehendner, Christoph M.

Circ Res ; 121(4): 368-375, 2017 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-28611075

10.

Long noncoding RNAs in organogenesis: making the difference.

Grote, Phillip; Herrmann, Bernhard G.

Trends Genet ; 31(6): 329-35, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25743487

11.

The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.

Werber, Martin; Wittler, Lars; Timmermann, Bernd; Grote, Phillip; Herrmann, Bernhard G.

Development ; 141(11): 2325-30, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24803591

12.

Different Concentrations of FGF Ligands, FGF2 or FGF8 Determine Distinct States of WNT-Induced Presomitic Mesoderm.

Sudheer, Smita; Liu, Jinhua; Marks, Matthias; Koch, Frederic; Anurin, Anna; Scholze, Manuela; Senft, Anna Dorothea; Wittler, Lars; Macura, Karol; Grote, Phillip; Herrmann, Bernhard G.

Stem Cells ; 34(7): 1790-800, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27038343

13.

Mechanisms of long noncoding RNA function in development and disease.

Schmitz, Sandra U; Grote, Phillip; Herrmann, Bernhard G.

Cell Mol Life Sci ; 73(13): 2491-509, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27007508

14.

Roles for long non-coding RNAs in physiology and disease.

Melissari, Maria-Theodora; Grote, Phillip.

Pflugers Arch ; 468(6): 945-58, 2016 06.

Artigo em Inglês | MEDLINE | ID: mdl-26944276

15.

DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer.

Grimm, Christina; Chavez, Lukas; Vilardell, Mireia; Farrall, Alexandra L; Tierling, Sascha; Böhm, Julia W; Grote, Phillip; Lienhard, Matthias; Dietrich, Jörn; Timmermann, Bernd; Walter, Jörn; Schweiger, Michal R; Lehrach, Hans; Herwig, Ralf; Herrmann, Bernhard G; Morkel, Markus.

PLoS Genet ; 9(2): e1003250, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23408899

16.

LncRNAs Coming of Age.

Grote, Phillip; Boon, Reinier A.

Circ Res ; 123(5): 535-537, 2018 08 17.

Artigo em Inglês | MEDLINE | ID: mdl-30355139

17.

Tpo1-mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response.

Krüger, Antje; Vowinckel, Jakob; Mülleder, Michael; Grote, Phillip; Capuano, Floriana; Bluemlein, Katharina; Ralser, Markus.

EMBO Rep ; 14(12): 1113-9, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24136413

18.

Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies.

Stegmann, Jil D; Kalanithy, Jeshurun C; Dworschak, Gabriel C; Ishorst, Nina; Mingardo, Enrico; Lopes, Filipa M; Ho, Yee Mang; Grote, Phillip; Lindenberg, Tobias T; Yilmaz, Öznur; Channab, Khadija; Seltzsam, Steve; Shril, Shirlee; Hildebrandt, Friedhelm; Boschann, Felix; Heinen, André; Jolly, Angad; Myers, Katherine; McBride, Kim; Bekheirnia, Mir Reza; Bekheirnia, Nasim; Scala, Marcello; Morleo, Manuela; Nigro, Vincenzo; Torella, Annalaura; Pinelli, Michele; Capra, Valeria; Accogli, Andrea; Maitz, Silvia; Spano, Alice; Olson, Rory J; Klee, Eric W; Lanpher, Brendan C; Jang, Se Song; Chae, Jong-Hee; Steinbauer, Philipp; Rieder, Dietmar; Janecke, Andreas R; Vodopiutz, Julia; Vogel, Ida; Blechingberg, Jenny; Cohen, Jennifer L; Riley, Kacie; Klee, Victoria; Walsh, Laurence E; Begemann, Matthias; Elbracht, Miriam; Eggermann, Thomas; Stoppe, Arzu; Stuurman, Kyra.

NPJ Genom Med ; 9(1): 18, 2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-38429302

19.

The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis.

Grote, Phillip; Herrmann, Bernhard G.

RNA Biol ; 10(10): 1579-85, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-24036695

20.

The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury in murine males.

Rogala, Sandra; Ali, Tamer; Melissari, Maria-Theodora; Währisch, Sandra; Schuster, Peggy; Sarre, Alexandre; Emídio, Rebeca Cordellini; Boettger, Thomas; Rogg, Eva-Maria; Kaur, Jaskiran; Krishnan, Jaya; Dumbovic, Gabrijela; Dimmeler, Stefanie; Ounzain, Samir; Pedrazzini, Thierry; Herrmann, Bernhard G; Grote, Phillip.

Nat Commun ; 14(1): 7024, 2023 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-37919291

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