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1.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190499, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713320

RESUMO

Sites suitable for the deployment of tidal turbines generally show a combination of complex seabed morphologies and extreme current magnitudes. Such configurations favour the formation of vortices, which can be very powerful. Anticipating the vortex effect on the turbine performance and/or lifespan requires refined description of the turbulence. Thanks to increased calculation resources, large-eddy simulation (LES) can now be applied to natural flow. An LES approach developed within the TELEMAC-3D open-source software is presented here. After validating the model with in-situ measurements, the model is applied to characterize the flow statistics of the Alderney Race. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

2.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190496, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713315

RESUMO

Two coupled four-beam acoustic Doppler current profilers were used to provide simultaneous and independent measurements of the turbulent kinetic energy (TKE) dissipation rate ε and the TKE production rate [Formula: see text] over a 36 h long period at a highly energetic tidal energy site in the Alderney Race. The eight-beam arrangement enabled the evaluation of the six components of the Reynolds stress tensor which allows for an improved estimation of the TKE production rate. Depth-time series of ε, [Formula: see text] and the Reynolds stresses are provided. The comparison between ε and [Formula: see text] was performed by calculating individual ratios of ε corresponding to [Formula: see text]. The depth-averaged ratio [Formula: see text] averaged over whole flood and ebb tide were found to be 2.2 and 2.8 respectively, indicating that TKE dissipation exceeds TKE production. It is shown that the term of diffusive transport of TKE is significant. As a result, non-local transport is important to the TKE budget and the common assumption of a local balance, i.e. a balance between production and dissipation, is not valid at the measurement site. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

3.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190495, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713316

RESUMO

A system of two coupled four-beam acoustic Doppler current profilers was used to collect turbulence measurements over a 36-h period at a highly energetic tidal energy site in Alderney Race. This system enables the evaluation of the six components of the Reynolds stress tensor throughout a large proportion of the water column. The present study provides mean vertical profiles of the velocity, the turbulence intensity and the integral lengthscale along the streamwise, spanwise and vertical direction of the tidal current. Based on our results and considering a tidal-stream energy convertor (TEC) aligned with the current main direction, the main elements of turbulence prone to affect the structure (material fatigue) and to alter power generation would likely be: (i) the streamwise turbulence intensity (Ix), (ii) the shear stress, [Formula: see text], (iii) the normal stress, [Formula: see text] and (iv) the vertical integral lengthscale (Lz). The streamwise turbulence intensity, (Ix), was found to be higher than that estimated at other tidal energy sites across the world for similar height above bottom. Along the vertical direction, the length (Lz) of the large-scale turbulence eddies was found to be equivalent to the rotor diameter of the TEC Sabella D10. It is considered that the turbulence metrics presented in this paper will be valuable for TECs designers, helping them optimize their designs as well as improve loading prediction through the lifetime of the machines. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

4.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190498, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713317

RESUMO

The tides are a predictable, renewable, source of energy that, if harnessed, can provide significant levels of electricity generation. The Alderney Race (AR), with current speeds that exceed 5 m s-1 during spring tides, is one of the most concentrated regions of tidal energy in the world, with the upper-bound resource estimated at 5.1 GW. Owing to its significance, the AR is frequently used for model case studies of tidal energy conversion, and here we review these model applications and outcomes. We examine a range of temporal and spatial modelling scales, from regional models applied to resource assessment and characterization, to more detailed models that include energy extraction and array optimization. We also examine a range of physical processes that influence the tidal energy resource, including the role of waves and turbulence in tidal energy resource assessment and loadings on turbines. The review discusses model validation, and covers a range of numerical modelling approaches, from two-dimensional to three-dimensional tidal models, two-way coupled wave-tide models, Large Eddy Simulation (LES) models, and the application of optimization techniques. The review contains guidance on model approaches and sources of data that can be used for future studies of the AR, or translated to other tidal energy regions. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

5.
Eur Phys J E Soft Matter ; 41(12): 146, 2018 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-30569329

RESUMO

Recent theories of drag reduction in wall turbulence assumed that the presence of the polymer leads to an effective viscosity, which increases linearly with the distance from the wall. Such a linear viscosity profile reduces the Reynolds stress (i.e., the momentum flux to the wall), which leads to drag reduction. For the usual flexible polymers employed in drag reduction, the effective viscosity is however a strongly non-linear effect that is difficult to quantify. We therefore investigate the turbulent drag reduction characteristics of a stiff rod-like polymer for which any effective viscosity changes are only due to the orientation of the polymers. The results show that close to the walls the polymers orient and the viscosity is low, whereas in the bulk the polymers are randomly oriented and the effective viscosity is high. This indeed leads to a reduction of the Reynolds stress and hence to a drag reduction.

6.
Blood ; 123(21): 3354-63, 2014 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-24553181

RESUMO

Interactions between platelet glycoprotein (Gp) IIb/IIIa and plasma proteins mediate platelet cross-linking in arterial thrombi. However, GpIIb/IIIa inhibitors fail to disperse platelet aggregates after myocardial infarction or ischemic stroke. These results suggest that stability of occlusive thrombi involves additional and as-yet-unidentified mechanisms. In the present study, we investigated the mechanisms driving platelet cross-linking during occlusive thrombus formation. Using computational fluid dynamic simulations and in vivo thrombosis models, we demonstrated that the inner structure of occlusive thrombi is heterogeneous and primarily determined by the rheological conditions that prevailed during thrombus growth. Unlike the first steps of thrombus formation, which are GpIIb/IIIa-dependent, our findings reveal that closure of the arterial lumen is mediated by GpIbα-von Willebrand Factor (VWF) interactions. Accordingly, disruption of platelet cross-linking using GpIbα-VWF inhibitors restored vessel patency and improved outcome in a mouse model of ischemic stroke, although the thrombi were resistant to fibrinolysis or traditional antithrombotic agents. Overall, our study demonstrates that disruption of GpIbα-VWF interactions restores vessel patency after occlusive thrombosis by specifically disaggregating the external layer of occlusive thrombi, which is constituted of platelet aggregates formed under very high shear rates.


Assuntos
Plaquetas/patologia , Complexo Glicoproteico GPIb-IX de Plaquetas/metabolismo , Trombose/metabolismo , Trombose/patologia , Fator de von Willebrand/metabolismo , Animais , Benzofuranos , Plaquetas/metabolismo , Vasos Sanguíneos/metabolismo , Vasos Sanguíneos/patologia , Hemorreologia , Masculino , Camundongos , Agregação Plaquetária , Mapas de Interação de Proteínas , Quinolinas
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