Detalhe da pesquisa
1.
Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.
Immunity
; 36(5): 769-81, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22608497
2.
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
J Immunol
; 199(7): 2249-2260, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28801357
3.
The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.
Clin Immunol
; 173: 171-180, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27816669
4.
Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.
J Immunol
; 188(1): 487-96, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22105996
5.
IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function.
JCI Insight
; 7(22)2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282595
6.
Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling.
J Immunol
; 182(6): 3343-7, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19265110
7.
Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
Diabetes
; 68(6): 1240-1250, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894366
8.
Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.
Diabetes
; 65(3): 794-802, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631741
9.
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
J Clin Invest
; 123(5): 2024-36, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23619366
10.
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity.
J Exp Med
; 205(12): 2899-913, 2008 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19015308
11.
Myc stimulates B lymphocyte differentiation and amplifies calcium signaling.
J Cell Biol
; 179(4): 717-31, 2007 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17998397
12.
IL-21: a novel IL-2-family lymphokine that modulates B, T, and natural killer cell responses.
J Allergy Clin Immunol
; 112(6): 1033-45, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14657853
13.
The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.
Biochemistry
; 41(27): 8725-31, 2002 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12093291