Detalhe da pesquisa
1.
Tuberculous meningitis: a roadmap for advancing basic and translational research.
Nat Immunol
; 19(6): 521-525, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29777209
2.
Pharmacokinetics of standard versus high-dose isoniazid for treatment of multidrug-resistant tuberculosis.
J Antimicrob Chemother
; 77(9): 2489-2499, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678468
3.
A Semimechanistic Model of the Bactericidal Activity of High-Dose Isoniazid against Multidrug-Resistant Tuberculosis: Results from a Randomized Clinical Trial.
Am J Respir Crit Care Med
; 204(11): 1327-1335, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34403326
4.
Early Bactericidal Activity of Different Isoniazid Doses for Drug-Resistant Tuberculosis (INHindsight): A Randomized, Open-Label Clinical Trial.
Am J Respir Crit Care Med
; 201(11): 1416-1424, 2020 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31945300
5.
Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with Tuberculosis.
Am J Respir Crit Care Med
; 194(12): 1532-1540, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27387272
6.
Reply to Decroo et al.: High-Dose First-Line Treatment Regimen for Recurrent Rifampicin-Susceptible Tuberculosis.
Am J Respir Crit Care Med
; 201(12): 1579-1580, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32130866
7.
Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious Diseases.
Clin Infect Dis
; 61Suppl 3: S200-16, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26409283
8.
Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers.
Antimicrob Agents Chemother
; 59(6): 3399-405, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25824215
9.
Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide.
Proc Natl Acad Sci U S A
; 109(37): 15001-5, 2012 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22927424
10.
New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future.
J Infect Dis
; 205 Suppl 2: S241-9, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22448022
11.
Innovative trial designs are practical solutions for improving the treatment of tuberculosis.
J Infect Dis
; 205 Suppl 2: S250-7, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22448027
12.
Clinical research and development of tuberculosis diagnostics: moving from silos to synergy.
J Infect Dis
; 205 Suppl 2: S159-68, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22476718
13.
CDC/NIH Workshop. Tuberculosis biomarker and surrogate endpoint research roadmap.
Am J Respir Crit Care Med
; 184(8): 972-9, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737585
14.
Tuberculosis.
N Engl J Med
; 368(8): 745-55, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23425167
15.
QT effects of bedaquiline, delamanid, or both in patients with rifampicin-resistant tuberculosis: a phase 2, open-label, randomised, controlled trial.
Lancet Infect Dis
; 21(7): 975-983, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587897
16.
The China tuberculosis clinical trials consortium network: a model for international TB clinical trials capacity building.
Infect Dis Poverty
; 9(1): 52, 2020 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414419
17.
Assessing whether isoniazid is essential during the first 14 days of tuberculosis therapy: a phase 2a, open-label, randomised controlled trial.
Lancet Microbe
; 1(2): e84-e92, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33834177
18.
Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus.
J Clin Invest
; 130(6): 2789-2799, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32420917
19.
Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop.
Curr HIV Res
; 18(1): 19-28, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31870268
20.
Viewpoint: Challenges and opportunities in tuberculosis research.
J Infect Dis
; 205 Suppl 2: S347-52, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22448021