Detalhe da pesquisa
1.
Identification of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one scaffolds as potent Lck inhibitors as anti-cancer agents.
Bioorg Med Chem Lett
; 102: 129645, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38316368
2.
A Convergent Total Synthesis of (+)-Ineleganolide.
J Am Chem Soc
; 145(14): 7763-7767, 2023 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36989438
3.
Three-Component Coupling Reactions Involving Arynes, Phosphites, and Aldehydes toward 3-Mono-Substituted Benzoxaphosphole 1-Oxides.
J Org Chem
; 88(13): 8465-8479, 2023 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224336
4.
Discovery of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one and 3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one derivatives as novel ENPP1 inhibitors.
Bioorg Med Chem Lett
; 75: 128947, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35995398
5.
Identification of novel pyrrolopyrimidine and pyrrolopyridine derivatives as potent ENPP1 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 2434-2451, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36069240
6.
Identification of highly selective type II kinase inhibitors with chiral peptidomimetic tails.
J Enzyme Inhib Med Chem
; 37(1): 1257-1277, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484863
7.
Enantioselective Allenoate-Claisen Rearrangement Using Chiral Phosphate Catalysts.
J Am Chem Soc
; 142(13): 6390-6399, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182422
8.
Catalytic enantioselective construction of quaternary stereocenters: assembly of key building blocks for the synthesis of biologically active molecules.
Acc Chem Res
; 48(3): 740-51, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25715056
9.
A mild and efficient approach to enantioenriched α-hydroxyethyl α,ß-unsaturated δ-lactams.
Tetrahedron Lett
; 57(21): 2233-2235, 2016 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27182092
10.
Nickel-Catalyzed Intramolecular C-O Bond Formation: Synthesis of Cyclic Enol Ethers.
Angew Chem Int Ed Engl
; 55(26): 7437-40, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159831
11.
Evolution of a unified, stereodivergent approach to the synthesis of communesin F and perophoramidine.
J Org Chem
; 80(1): 528-47, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25402459
12.
Stereochemical evaluation of bis(phosphine) copper catalysts for the asymmetric alkylation of 3-bromooxindoles with α-arylated malonate esters.
Tetrahedron
; 71(22): 3666-3670, 2015 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25983348
13.
A New Method for the Cleavage of Nitrobenzyl Amides and Ethers.
Tetrahedron Lett
; 55(47): 6467-6469, 2014 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25400299
14.
Implications for Combination Therapy of Selective Monoamine Reuptake Inhibitors on Dopamine Transporters.
Biomedicines
; 11(10)2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37893219
15.
Chiroptical Synaptic Heterojunction Phototransistors Based on Self-Assembled Nanohelix of π-Conjugated Molecules for Direct Noise-Reduced Detection of Circularly Polarized Light.
Adv Sci (Weinh)
; 10(27): e2304039, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501319
16.
Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
J Med Chem
; 66(22): 15141-15170, 2023 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37963811
17.
Synthetic Strategy for Aryl(alkynyl)phosphinates by a Three-Component Coupling Reaction Involving Arynes, Phosphites, and Alkynes.
Org Lett
; 24(45): 8295-8299, 2022 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342701
18.
Synthesis of Benzoxaphosphole 1-Oxide Heterocycles via a Three-Component Coupling Reaction Involving Arynes, Phosphites, and Ketones.
Org Lett
; 24(11): 2192-2196, 2022 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285641
19.
A Synthetic Strategy toward Eight-Membered Cyclic Amines by Cycloetherification and Claisen Rearrangement.
Org Lett
; 23(9): 3300-3303, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33844548
20.
Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.
Eur J Med Chem
; 101: 716-35, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26218650