Detalhe da pesquisa
1.
Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.
PLoS Pathog
; 17(7): e1009682, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293063
2.
Activation of transient receptor potential channel Sm.(Schistosoma mansoni)TRPMPZQ by PZQ, enhanced Ca++ influx, spastic paralysis, and tegumental disrupture-the deadly cascade in parasitic schistosomes, other trematodes, and cestodes.
Parasitol Res
; 119(8): 2371-2382, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32607709
3.
SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.
PLoS Pathog
; 7(4): e1001330, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21490955
4.
In vivo efficacy of PF1022A and nicotinic acetylcholine receptor agonists alone and in combination against Nippostrongylus brasiliensis.
Parasitology
; 140(10): 1252-65, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23742764
5.
In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis.
Parasitol Res
; 112(1): 335-45, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23052772
6.
Praziquantel - 50 Years of Research.
ChemMedChem
; 18(12): e202300154, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37009677
7.
Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans.
Mol Pharmacol
; 79(6): 1031-43, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415309
8.
Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo.
Parasitology
; 138(9): 1193-201, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21756418
9.
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside.
Int J Parasitol Drugs Drug Resist
; 17: 27-35, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339934
10.
FMRFamide-like neuropeptides as putative ligands of the latrophilin-like HC110-R from Haemonchus contortus.
Mol Biochem Parasitol
; 164(2): 162-4, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19126419
11.
The putative cyclooctadepsipeptide receptor depsiphilin of the canine hookworm Ancylostoma caninum.
Parasitol Res
; 105 Suppl 1: S91-100, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19575230
12.
Standardization of the egg hatch test for the detection of benzimidazole resistance in parasitic nematodes.
Parasitol Res
; 105(3): 825-34, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19452165
13.
Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans.
Curr Biol
; 14(15): 1374-9, 2004 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15296755
14.
Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans.
Int J Parasitol
; 37(6): 627-36, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17157854
15.
The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans.
Int J Parasitol
; 37(14): 1577-88, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17583712
16.
SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics.
Invert Neurosci
; 7(4): 199-208, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17962986
17.
A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.
J Antibiot (Tokyo)
; 58(1): 50-5, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15813180
18.
The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits.
PLoS Negl Trop Dis
; 9(10): e0004062, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437177
19.
PF1022A and related cyclodepsipeptides - a novel class of anthelmintics.
Curr Top Med Chem
; 2(7): 759-77, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12052189
20.
Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action.
Int J Antimicrob Agents
; 22(3): 318-31, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-13678839