Detalhe da pesquisa
1.
Transcriptional Profiling and Consensus Molecular Subtype Assignment to Understand Response and Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Colorectal Cancer.
JCO Precis Oncol
; 7: e2200422, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487150
2.
Oncogene addiction to GNAS in GNASR201 mutant tumors.
Oncogene
; 41(35): 4159-4168, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35879396
3.
Red blood cell permeabilization by hypotonic treatments, saponin, and anticancer avicins.
Biochim Biophys Acta
; 1798(6): 1189-96, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346345
4.
Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery.
J Clin Invest
; 113(1): 65-73, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14702110
5.
Avicins, a novel plant-derived metabolite lowers energy metabolism in tumor cells by targeting the outer mitochondrial membrane.
Mitochondrion
; 7(3): 234-40, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17317337
6.
Triterpenoid electrophiles (avicins) suppress heat shock protein-70 and x-linked inhibitor of apoptosis proteins in malignant cells by activation of ubiquitin machinery: implications for proapoptotic activity.
Clin Cancer Res
; 11(5): 1953-62, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15756021
7.
Mitochondria as integrators of information in an early-evolving animal: insights from a triterpenoid metabolite.
Proc Biol Sci
; 272(1562): 527-31, 2005 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15799949
8.
Metabolomics of plant saponins: bioprospecting triterpene glycoside diversity with respect to mammalian cell targets.
OMICS
; 6(3): 235-46, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12427275
9.
The anticancer plant triterpenoid, avicin D, regulates glucocorticoid receptor signaling: implications for cellular metabolism.
PLoS One
; 6(11): e28037, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22132201
10.
Natural triterpenoid avicins selectively induce tumor cell death.
Commun Integr Biol
; 3(3): 205-8, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20714394
11.
Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts.
PLoS One
; 4(12): e8532, 2009 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-20046832
12.
Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.
PLoS One
; 4(5): e5578, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19440292
13.
Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells.
J Invest Dermatol
; 128(11): 2728-2735, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18496567
14.
Avicins, natural anticancer saponins, permeabilize mitochondrial membranes.
Arch Biochem Biophys
; 454(2): 114-22, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16962987
15.
Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress.
Proc Natl Acad Sci U S A
; 102(29): 10088-93, 2005 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16030151
16.
Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast.
Proc Natl Acad Sci U S A
; 102(36): 12771-6, 2005 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16118282
17.
Proapoptotic triterpene electrophiles (avicins) form channels in membranes: cholesterol dependence.
Biophys J
; 88(4): 2577-84, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15653745
18.
Isolation and structures of avicins D and G: in vitro tumor-inhibitory saponins derived from Acacia victoriae.
J Nat Prod
; 66(6): 779-83, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12828461