Detalhe da pesquisa
1.
Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases.
Proc Natl Acad Sci U S A
; 120(48): e2310522120, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37983497
2.
Targeted Genome Mining Reveals the Biosynthetic Gene Clusters of Natural Product CYP51 Inhibitors.
J Am Chem Soc
; 143(16): 6043-6047, 2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33857369
3.
Anti-cryptococcal activity of preussolides A and B, phosphoethanolamine-substituted 24-membered macrolides, and leptosin C from coprophilous isolates of Preussia typharum.
J Ind Microbiol Biotechnol
; 48(9-10)2021 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33640980
4.
A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.
J Biol Chem
; 294(4): 1257-1266, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514758
5.
Acrophiarin (antibiotic S31794/F-1) from Penicillium arenicola shares biosynthetic features with both Aspergillus- and Leotiomycete-type echinocandins.
Environ Microbiol
; 22(6): 2292-2311, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32239586
6.
Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain.
Angew Chem Int Ed Engl
; 56(32): 9556-9560, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28679030
7.
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.
Fungal Genet Biol
; 89: 18-28, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808821
8.
Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Cell Chem Biol
; 30(11): 1453-1467.e8, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607550
9.
Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket.
J Am Chem Soc
; 134(29): 12259-65, 2012 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22741553
10.
Identification of the Antifungal Metabolite Chaetoglobosin P From Discosia rubi Using a Cryptococcus neoformans Inhibition Assay: Insights Into Mode of Action and Biosynthesis.
Front Microbiol
; 11: 1766, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32849391
11.
HEx: A heterologous expression platform for the discovery of fungal natural products.
Sci Adv
; 4(4): eaar5459, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29651464
12.
Turning the world's DNA into new medicines.
Trends Biotechnol
; 40(6): 766-767, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232575
13.
Improved precursor-directed biosynthesis in E. coli via directed evolution.
J Antibiot (Tokyo)
; 64(1): 59-64, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081955