Detalhe da pesquisa
1.
Temperature-dependent intracellular crystallization of firefly luciferase in mammalian cells is suppressed by D-luciferin and stabilizing inhibitors.
Exp Cell Res
; 440(1): 114131, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38876374
2.
Simultaneous induction of distinct protein phase separation events in multiple subcellular compartments of a single cell.
Exp Cell Res
; 379(1): 92-109, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851242
3.
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.
PLoS Genet
; 13(3): e1006659, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273074
4.
Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution.
Exp Cell Res
; 370(2): 208-226, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29940176
5.
Topogenesis and cell surface trafficking of GPR34 are facilitated by positive-inside rule that effects through a tri-basic motif in the first intracellular loop.
Biochim Biophys Acta
; 1863(7 Pt A): 1534-51, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27086875
6.
A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism.
J Biol Chem
; 290(12): 7535-62, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583986
7.
Modulation of in vivo IgG crystallization in the secretory pathway by heavy chain isotype class switching and N-linked glycosylation.
Biochim Biophys Acta
; 1843(7): 1325-38, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24703881
8.
Understanding the biosynthesis of human IgM SAM-6 through a combinatorial expression of mutant subunits that affect product assembly and secretion.
PLoS One
; 19(6): e0291568, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38848420
9.
Hair-follicle associated pluripotent (HAP)-cell-sheet implantation enhanced wound healing in diabetic db/db mice.
PLoS One
; 19(6): e0304676, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38875234
10.
Russell body inducing threshold depends on the variable domain sequences of individual human IgG clones and the cellular protein homeostasis.
Biochim Biophys Acta
; 1823(10): 1643-57, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22728328
11.
R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed.
Biol Cell
; 104(7): 397-417, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22443861
12.
In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells.
J Biol Chem
; 286(22): 19917-31, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21464137
13.
Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Exp Cell Res
; 317(7): 976-93, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21182835
14.
Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein.
Cytokine
; 53(1): 74-83, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20926308
15.
Light chain subunit of a poorly soluble human IgG2λ crystallizes in physiological pH environment both in cellulo and in vitro.
Biochim Biophys Acta Mol Cell Res
; 1868(9): 119078, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34118277
16.
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Mol Biol Cell
; 14(2): 698-720, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12589064
17.
Intermolecular interactions involving an acidic patch on immunoglobulin variable domain and the γ2 constant region mediate crystalline inclusion body formation in the endoplasmic reticulum.
Cell Logist
; 7(3): e1361499, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28944095
18.
Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic.
MAbs
; 9(5): 854-873, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379093
19.
Overexpression of cryoglobulin-like single-chain antibody induces morular cell phenotype via liquid-liquid phase separation in the secretory pathway organelles.
FEBS J
; 282(15): 2777-95, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26036200
20.
Russell body phenotype is preferentially induced by IgG mAb clones with high intrinsic condensation propensity: relations between the biosynthetic events in the ER and solution behaviors in vitro.
MAbs
; 6(6): 1518-32, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25484054