Easy access to polyhalogenated biaryls: regioselective (di)halogenation of hypervalent bromines and chlorines.

Polyhalogenated biaryls are unique motifs offering untapped potential as versatile building blocks for the expedient synthesis of complex biaryl compounds. Overcoming the limitations of conventional syntheses, we introduce a novel, metal-free, operationally simple and one-pot approach to regioselectively (di)halogenate biaryl compounds under mild conditions using cyclic biaryl hypervalent bromine and chlorine substrates as masked arynes. Through chemoselective post-functionalizations, these valuable products can expand the toolbox for synthesizing biaryl-containing scaffolds, addressing a critical gap in the field.

Micellar catalysis: a green solution to enable undirected and mild C-H activation of (oligo)thiophenes at the challenging ß-position.

The unexpected potential of micellar medium to achieve challenging ß-selective direct arylation of (oligo)thiophenes is reported. Thanks to the use of a water/surfactant solution in combination with natural feedstock-derived undecanoic acid as an additive, this high-yielding C-H coupling could be performed regioselectively at room temperature.