Detalhe da pesquisa
1.
Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision.
Proc Natl Acad Sci U S A
; 119(29): e2117090119, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858306
2.
Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers.
PLoS Biol
; 19(2): e3001138, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621242
3.
Insights into the structure-activity relationship of the anticancer compound ZJ-101: A role played by the amide moiety.
Bioorg Med Chem Lett
; 105: 129741, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38599296
4.
Synthesis and biological evaluation of biotinylated ZJ-101.
Bioorg Med Chem Lett
; 91: 129372, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37301523
5.
Modulation of the Endomembrane System by the Anticancer Natural Product Superstolide/ZJ-101.
Int J Mol Sci
; 24(11)2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298526
6.
robustica: customizable robust independent component analysis.
BMC Bioinformatics
; 23(1): 519, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36471244
7.
ProteinFishing: a protein complex generator within the ModelX toolsuite.
Bioinformatics
; 36(14): 4208-4210, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32437555
8.
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.
Proc Natl Acad Sci U S A
; 112(52): E7276-85, 2015 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26655341
9.
Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety.
Bioorg Med Chem Lett
; 26(15): 3411-3, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27374243
10.
Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety.
Bioorg Med Chem Lett
; 26(19): 4702-4704, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27595422
11.
Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring.
Bioorg Med Chem Lett
; 26(12): 2890-2892, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27133592
12.
Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation.
Angew Chem Int Ed Engl
; 55(39): 12035-9, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27574181
13.
Comparison of dose selection based on target engagement versus inhibition of receptor-ligand interaction for checkpoint inhibitors.
CPT Pharmacometrics Syst Pharmacol
; 13(6): 919-925, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38790133
14.
Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors.
ACS Med Chem Lett
; 11(6): 1111-1117, 2020 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32550989
15.
Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition.
J Med Chem
; 61(24): 11158-11168, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30481027
16.
Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways.
Cancer Manag Res
; 10: 4817-4829, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425575
17.
Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking.
Int J Biol Sci
; 14(10): 1175-1185, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30123067
18.
Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP).
Antiviral Res
; 156: 55-63, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29807040
19.
Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.
ACS Chem Biol
; 12(1): 174-182, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28103683
20.
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.
Cancer Lett
; 409: 91-103, 2017 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923401