Detalhe da pesquisa
1.
Endoplasmic reticulum protein BI-1 regulates Ca²âº-mediated bioenergetics to promote autophagy.
Genes Dev
; 26(10): 1041-54, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22588718
2.
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Proc Natl Acad Sci U S A
; 108(21): 8785-90, 2011 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21555592
3.
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
J Cell Physiol
; 227(5): 2145-53, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21780116
4.
Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma.
Cancer Cell
; 5(6): 565-74, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15193259
5.
Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics.
J Cell Physiol
; 226(10): 2484-93, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21792905
6.
Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.
Mol Cancer Ther
; 7(11): 3519-26, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19001435
7.
Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.
Cancer Biol Ther
; 13(6): 349-57, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22313636
8.
Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.
Anticancer Agents Med Chem
; 12(9): 1143-55, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22931411
9.
Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480.
Cancer Res
; 71(21): 6601-10, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21920898
10.
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development.
ACS Chem Biol
; 6(5): 432-43, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21226522
11.
Targeting Mcl-1 for the therapy of cancer.
Expert Opin Investig Drugs
; 20(10): 1397-411, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21851287
12.
Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.
Mol Cancer Res
; 8(1): 35-45, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20053726
13.
Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
Mol Cancer Ther
; 9(4): 953-62, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371721
14.
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.
Cancer Cell
; 16(6): 487-97, 2009 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19962667