1.
J Org Chem
; 87(14): 9375-9383, 2022 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35776916
RESUMO
A versatile strategy to halogenated xanthones was developed that relies on a modular coupling of vanillin derivatives with a dibromoquinone. Depending on the reaction conditions, either the 6- or the 7-bromo heterocycles may be obtained in a divergent manner. These heterocycles may be readily further elaborated by sequential Sonogashira couplings, and the sequence may be successfully applied to substructures of the antibiotic lysolipin.