Detalhe da pesquisa
1.
Rhenium and technetium complexes of thioamide derivatives of pyridylhydrazine that bind to amyloid-ß plaques.
J Biol Inorg Chem
; 23(7): 1139-1151, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29982869
2.
Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
J Neurosci
; 34(23): 8021-31, 2014 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899723
3.
Zn II(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism.
Neurobiol Dis
; 81: 20-4, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25766674
4.
Intracellular distribution of fluorescent copper and zinc bis(thiosemicarbazonato) complexes measured with fluorescence lifetime spectroscopy.
Inorg Chem
; 54(19): 9556-67, 2015 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26397162
5.
Diagnostic imaging agents for Alzheimer's disease: copper radiopharmaceuticals that target Aß plaques.
J Am Chem Soc
; 135(43): 16120-32, 2013 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24070589
6.
Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model.
J Biol Chem
; 286(51): 44035-44044, 2011 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22033929
7.
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.
J Am Chem Soc
; 130(38): 12570-1, 2008 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18729360
8.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Acta Neuropathol Commun
; 2: 25, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24581221
9.
Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis.
Amyotroph Lateral Scler Frontotemporal Degener
; 14(7-8): 586-90, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23952668
10.
Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis.
PLoS One
; 8(3): e58644, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23516525
11.
Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3ß inhibition due to intracellular delivery of copper.
Dalton Trans
; 40(6): 1338-47, 2011 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21173986
12.
Cationic, linear Au(I) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity.
Dalton Trans
; (30): 3708-15, 2006 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16865184
13.
Synthetic, structural and spectroscopic studies of (pseudo)halo(1,3-di-tert-butylimidazol-2-ylidine)gold complexes.
Dalton Trans
; (1): 37-43, 2005 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15605145