Detalhe da pesquisa
1.
Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.
Blood
; 112(8): 3434-43, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18474728
2.
Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance.
Cancer Res
; 67(9): 4459-66, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17483361
3.
Inhibition of p38alpha mitogen-activated protein kinase prevents the development of osteolytic bone disease, reduces tumor burden, and increases survival in murine models of multiple myeloma.
Cancer Res
; 67(10): 4572-7, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17495322
4.
p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation.
J Pharmacol Exp Ther
; 324(3): 921-9, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18056868
5.
Pyrimidine-based inhibitors of CaMKIIdelta.
Bioorg Med Chem Lett
; 18(7): 2404-8, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18334293
6.
p38alpha-selective MAP kinase inhibitor reduces tumor growth in mouse xenograft models of multiple myeloma.
Anticancer Res
; 28(6A): 3827-33, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189670
7.
Role of p38 mitogen activated protein kinase in a model of osteosarcoma-induced pain.
Pharmacol Biochem Behav
; 90(4): 664-75, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18584857
8.
Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinase.
Pharmacology
; 81(3): 204-20, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18176091
9.
Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.
Cancer Res
; 66(13): 6763-71, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16818652
10.
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Neuro Oncol
; 9(3): 259-70, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17522330
11.
Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.
Anticancer Res
; 27(6B): 4149-57, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229422
12.
Basic mechanisms responsible for osteolytic and osteoblastic bone metastases.
Clin Cancer Res
; 12(20 Pt 2): 6213s-6216s, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17062703
13.
A p38 mitogen-activated protein kinase inhibitor arrests active alveolar bone loss in a rat periodontitis model.
J Periodontol
; 78(10): 1992-8, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18062121
14.
Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease.
Nat Clin Pract Cardiovasc Med
; 3(8): 437-45, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16874356
15.
Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness.
Eur J Pharmacol
; 544(1-3): 160-7, 2006 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16843456
16.
SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo.
Cancer Res
; 64(21): 7954-61, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15520202
17.
p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells.
Oncogene
; 23(54): 8766-76, 2004 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15480425
18.
Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment.
Clin Cancer Res
; 10(22): 7540-6, 2004 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15569984
19.
Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility.
Stroke
; 33(7): 1905-10, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12105373
20.
Can a selective PPARγ modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone?
Diabetes Care
; 37(7): 1918-23, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24722496