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2.
Eur Radiol ; 25(1): 267-73, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25163903

RESUMO

OBJECTIVE: To assess patients' outcomes after subacromial or glenohumeral injections based on the degree of lateral extension of the acromion. METHODS: 307 patients were prospectively included after therapeutic fluoroscopy-guided subacromial (n = 148) or glenohumeral (n = 159) injections with anaesthetic and long-acting corticosteroids. Pre- and post-injection outcomes at 1 week and 1 month were obtained using the 11-point numerical rating scale (NRS) for pain. Lateral extension of the acromion was quantified and categorized by the critical shoulder angle (CSA) and the acromion index (AI) on anteroposterior conventional radiographs. RESULTS: Patients' outcomes at 1 week and 1 month were significantly improved (p < 0.001) compared to baseline for subacromial and glenohumeral injection patients. Patients with a CSA <35° showed significantly higher pain reduction 1 month after subacromial injection compared to patients with a CSA >35° (4.2 ± 2.6 vs. 3.2 ± 3.0, p = 0.04). A significant difference in the 1-month NRS change in pain scores is noted for smaller AIs after subacromial injection (4.3 ± 2.8 vs. 2.6 ± 2.9; p = 0.01). No significant association was noted between clinical outcome and the lateral extension of the acromion after glenohumeral joint injections. CONCLUSIONS: A short lateral extension of the acromion was associated with better clinical outcomes in subacromial injection patients but not in glenohumeral injection patients. KEY POINTS: • Patients' outcomes at 1 month improved significantly compared to baseline for subacromial injections. • Patients' outcomes at 1 month improved significantly compared to baseline for glenohumeral injections. • Short acromial lateralization was associated with better clinical outcome after subacromial injection. • The acromial lateralization was not associated with clinical outcome after glenohumeral injection.


Assuntos
Acrômio/diagnóstico por imagem , Síndrome de Colisão do Ombro/tratamento farmacológico , Triancinolona/administração & dosagem , Adulto , Feminino , Seguimentos , Glucocorticoides/administração & dosagem , Humanos , Injeções Intra-Articulares , Masculino , Estudos Prospectivos , Curva ROC , Radiografia , Síndrome de Colisão do Ombro/diagnóstico por imagem , Articulação do Ombro , Resultado do Tratamento
3.
BMC Musculoskelet Disord ; 16: 234, 2015 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-26338033

RESUMO

BACKGROUND: Modic changes (MC) have been linked with low back pain (LBP) and worse outcomes from some treatments. No studies have investigated the impact that MCs may have on patient outcomes from lumbar facet injections. Therefore, the purpose of this study is to investigate whether the presence of Modic changes is related to 'improvement' in patients undergoing imaging-guided lumbar facet injection therapy. METHODS: Outcomes from 226 patients with MRI scans within 3 months of their imaging-guided lumbar facet injections were investigated to determine whether MCs are related to 'improvement' post injection. At 1 day, 1 week and 1 month post injection the Patients Global Impression of Change scale answers were collected by postal questionnaire. This was the primary outcome measure. The numerical rating scale for pain data was collected prior to treatment and at the same post injection time points. The MRI scans were independently evaluated by two examiners for the presence/absence of Modic changes and the type of Modic change if present. Kappa statistics were used for reliability of diagnosis analysis. Chi-squared test and logistic regression analysis tested MCs with 'improvement'. RESULTS: Intra- and inter-examiner reliability for the diagnosis of MCs was Kappa = 0.77 and 0.74. Intra- and inter-examiner reliability for categorizing MCs was K = 0.77 and K = 0.78. At 1 month post injection 45.2 % of patients without MCs reported clinically relevant 'improvement' compared to 34.2 % of patients with MC I and 32.1 % of patients with MC II. However, this did not reach statistical significance. Logistic regression found that Modic changes were not predictive of 'improvement'. CONCLUSIONS: There was a tendency for patients without MCs to have better outcomes but this did not reach statistical significance. The reliability of diagnosing MCs was substantial.


Assuntos
Dor Lombar/diagnóstico , Vértebras Lombares/patologia , Imageamento por Ressonância Magnética/tendências , Medição da Dor/tendências , Articulação Zigapofisária/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Anestésicos Locais/administração & dosagem , Anti-Inflamatórios/administração & dosagem , Estudos de Coortes , Feminino , Humanos , Injeções Intra-Articulares , Dor Lombar/tratamento farmacológico , Vértebras Lombares/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Medição da Dor/efeitos dos fármacos , Medição da Dor/métodos , Estudos Prospectivos , Adulto Jovem , Articulação Zigapofisária/efeitos dos fármacos
4.
Radiology ; 271(1): 172-82, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24475792

RESUMO

PURPOSE: To provide normal values of the cervical spinal canal and spinal cord dimensions in several planes with respect to spinal level, age, sex, and body height. MATERIALS AND METHODS: This study was approved by the institutional review board; all individuals provided signed informed consent. In a prospective multicenter study, two blinded raters independently examined cervical spine magnetic resonance (MR) images of 140 healthy volunteers who were white. The midsagittal diameters and areas of spinal canal and spinal cord, respectively, were measured at the midvertebral levels of C1, C3, and C6. A multivariate general linear model described the influence of sex, body height, age, and spinal level on the measured values. RESULTS: There were differences for sex, spinal level, interaction between sex and level, and body height, while age had significant yet limited influence. Normative ranges for the sagittal diameters and areas of spinal canal and spinal cord were defined at C1, C3, and C6 levels for men and women. In addition to a calculation of normative ranges for a specific sex, spinal level, age, and body height data, data for three different height subgroups at 45 years of age were extracted. These results show a range of the spinal canal dimensions at C1 (from 10.7 to 19.7 mm), C3 (from 9.4 to 17.2 mm), and C6 (from 9.2 to 16.8 mm) levels. CONCLUSION: The dimensions of the cervical spinal canal and cord in healthy individuals are associated with spinal level, sex, age, and height. Online supplemental material is available for this article.


Assuntos
Vértebras Cervicais/anatomia & histologia , Imageamento por Ressonância Magnética/métodos , Canal Medular/anatomia & histologia , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Valores de Referência , Inquéritos e Questionários , Suíça
5.
AJR Am J Roentgenol ; 202(1): 160-9, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24370140

RESUMO

OBJECTIVE: The objective of our study was to prospectively compare the diagnostic performance of MR arthrography and conventional MRI with surgical correlation in the same patient for detecting labrum and articular cartilage defects. SUBJECTS AND METHODS: Twenty-eight patients (mean age, 31.8 years) underwent MR arthrography, conventional MRI, and subsequent hip surgery, which served as the reference standard. Labrum and cartilage defects were evaluated at MRI by two independent readers. A McNemar test and kappa statistics were used for statistical analysis. RESULTS: At surgery, 31 labral tears were identified. MR arthrography had an advantage over conventional MRI for detecting labral tears at the anterosuperior quadrant (sensitivity of MR arthrography, 81% and 69% for readers 1 and 2, respectively; sensitivity of conventional MRI, 50% for both readers); this difference in performance between MR arthrography and conventional MRI was statistically significant for reader 1 (p = 0.02) but not for reader 2 (p = 0.2). Interobserver agreement for labral tears was higher for MR arthrography (κ = 0.81) than for conventional MRI (κ = 0.63). Surgery showed 31 acetabular cartilage defects and nine femoral cartilage defects. MR arthrography had an advantage over conventional MRI for detecting acetabular cartilage defects (sensitivity of MR arthrography, 71% and 92% for readers 1 and 2, respectively; sensitivity of conventional MRI, 58% and 83%), whereas there was no advantage to using MR arthrography for detecting femoral cartilage defects with statistically significant difference for the acetabular cartilage or femoral cartilage. Interobserver agreement was slightly higher for MR arthrography (κ = 0.50) than for conventional MRI (κ = 0.40) for assessing the acetabular cartilage and was almost identical for the femoral cartilage (κ = 0.62 and 0.63, respectively). CONCLUSION: MR arthrography was superior to conventional MRI for detecting labral tears and acetabular cartilage defects and showed a higher interobserver agreement. For femoral cartilage lesions, both modalities yielded comparable results.


Assuntos
Cartilagem Articular/patologia , Meios de Contraste/administração & dosagem , Impacto Femoroacetabular/diagnóstico , Impacto Femoroacetabular/cirurgia , Articulação do Quadril/patologia , Imageamento por Ressonância Magnética/métodos , Adolescente , Adulto , Artroscopia , Cartilagem Articular/cirurgia , Feminino , Articulação do Quadril/cirurgia , Humanos , Interpretação de Imagem Assistida por Computador , Injeções Intra-Articulares , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento
6.
Skeletal Radiol ; 43(7): 979-84, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24737087

RESUMO

OBJECTIVES: To present the process of creating an imaging-guided injections outcomes database and to reflect on how this database has affected the scientific activities of the radiology department. MATERIALS AND METHODS: The literature was searched to identify studies on the effectiveness of musculoskeletal therapeutic injections, areas where research is lacking, and relevant outcome measures. Validated outcome measures were chosen and tested in a pilot study. Data collection time points of 1 day, 1 week and 1 month post-injection were determined and the post-pilot study postal questionnaires were created. The data collection process began and has been ongoing for over 4 years. Critical reflection on the process and outcomes from the database occurred. RESULTS: The 9 steps to creating this outcomes database are presented. The numerical rating scale for pain (NRS) and the Patient's Global Impression of Change (PGIC) were identified as the most valid, reliable, and time-effective outcome measures. At most, 50% of patients return their postal questionnaire. The database has facilitated the publication of numerous research projects. CONCLUSIONS: Setting up an outcomes database is straightforward and productive. The NRS and PGIC were considered the most useful outcome measures. This database facilitated critical reflection on current practice and provides the foundation for several research studies.


Assuntos
Bases de Dados Factuais , Injeções Intra-Articulares/estatística & dados numéricos , Artropatias/tratamento farmacológico , Artropatias/epidemiologia , Avaliação de Resultados em Cuidados de Saúde/estatística & dados numéricos , Medição da Dor/estatística & dados numéricos , Radiografia Intervencionista/estatística & dados numéricos , Humanos , Avaliação de Resultados em Cuidados de Saúde/métodos , Medição da Dor/métodos , Projetos Piloto , Prevalência , Sistema de Registros , Resultado do Tratamento
7.
Eur Radiol ; 23(9): 2594-601, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23579419

RESUMO

OBJECTIVE: To investigate the ability of coronal non-weight-bearing MR images to discriminate between normal and abnormal hindfoot alignment. METHODS: Three different measurement techniques (calcaneal axis, medial/lateral calcaneal contour) based on weight-bearing hindfoot alignment radiographs were applied in 49 patients (mean, 48 years; range 21-76 years). Three groups of subjects were enrolled: (1) normal hindfoot alignment (0°-10° valgus); (2) abnormal valgus (>10°); (3) any degree of varus hindfoot alignment. Hindfoot alignment was then measured on coronal MR images using four different measurement techniques (calcaneal axis, medial/lateral calcaneal contour, sustentaculum tangent). ROC analysis was performed to find the MR measurement with the greatest sensitivity and specificity for discrimination between normal and abnormal hindfoot alignment. RESULTS: The most accurate measurement on MR images to detect abnormal hindfoot valgus was the one using the medial calcaneal contour, reaching a sensitivity/specificity of 86 %/75 % using a cutoff value of >11° valgus. The most accurate measurement on MR images to detect abnormal hindfoot varus was the sustentaculum tangent, reaching a sensitivity/specificity of 91 %/71 % using a cutoff value of <12° valgus. CONCLUSION: It is possible to suspect abnormal hindfoot alignment on coronal non-weight-bearing MR images. KEY POINTS: • Abnormal hindfoot alignment can be identified on coronal non-weight-bearing MR images. • The sustentaculum tangent was the best predictor of an abnormally varus hindfoot. • The medial calcaneal contour was the best predictor of a valgus hindfoot.


Assuntos
Calcâneo/patologia , Deformidades do Pé/patologia , Pé/fisiopatologia , Imageamento por Ressonância Magnética/métodos , Adulto , Idoso , Algoritmos , Calcâneo/diagnóstico por imagem , Feminino , Pé/diagnóstico por imagem , Deformidades do Pé/diagnóstico por imagem , Humanos , Processamento de Imagem Assistida por Computador/métodos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Curva ROC , Radiografia , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Suporte de Carga , Adulto Jovem
8.
AJR Am J Roentgenol ; 201(5): W735-46, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24147503

RESUMO

OBJECTIVE: The objective of our study was to perform a systematic review of the semiquantitative and qualitative radiologic criteria that are used for the diagnosis of lumbar spinal stenosis (LSS). MATERIALS AND METHODS: A four-step systematic literature search including the MEDLINE database was performed by an experienced librarian to reveal all semiquantitative or qualitative radiologic criteria used for the diagnosis of LSS. The precise definitions of all criteria, normal or abnormal values (if applicable), and intra- and interrater reliability were noted by two independent readers. Descriptive statistics were used. RESULTS: A total of 14 semiquantitative or qualitative radiologic parameters were identified and distinguished according to relevant anatomic spaces into criteria for central canal stenosis, lateral (recess) stenosis, and foraminal stenosis. Great variability in terms of the exact definitions of the criteria was found. For 10 of the 14 criteria, the intra- and interrater reliability data were found with kappa values ranging from 0.01 to 1.0. CONCLUSION: Our systematic literature review identified 14 different semiquantitative or qualitative radiologic criteria that are used for the diagnosis of LSS; however, these criteria show remarkable variability in terms of their exact individual definitions and intra- and interrater reliability.


Assuntos
Diagnóstico por Imagem , Vértebras Lombares , Estenose Espinal/diagnóstico , Humanos
9.
AJR Am J Roentgenol ; 201(4): 865-71, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24059377

RESUMO

OBJECTIVE: The purpose of this study was to compare abnormalities detected on conventional shoulder radiography with improvement in pain and shoulder function after subacromial injections. SUBJECTS AND METHODS: We conducted a prospective outcomes study including 98 consecutive patients after fluoroscopy-guided subacromial injections who returned outcome questionnaires and who underwent routine shoulder radiography. Numeric pain rating scale (NRS) data were collected before and, along with patient global impression of change (PGIC) data, at 1 week and 1 month after injection. Outcome differences were assessed using the Student t test and Mann-Whitney U test. Logistic regression analysis was done, including radiographic variables compared with the outcome improvement. The odds ratios with 95% CIs were identified for the significant predictors. RESULTS: A significant difference in overall improvement was found depending on the posterior acromial slope. Patients with a slope of more than 36° had significantly lower NRS and PGIC scores at 1 week and 1 month (p < 0.025) compared with those with a slope of 36° or less, with 86.4% of patients with a slope of more than 36° reporting significant improvement at 1 month. This was the only variable linked with improvement in the logistic regression analysis, with an odds ratio of 2.16 (95% CI, 1.11-4.22). Patients with calcific tendinitis had significantly lower NRS scores at both 1 week and 1 month (p = 0.03 and 0.05, respectively) and PGIC scores at 1 week (p = 0.05). CONCLUSION: A posterior acromial slope of more than 36° and the presence of calcific tendinitis on conventional shoulder radiography are associated with better outcomes. Patients with a slope of more than 36° showed the best improvement.


Assuntos
Corticosteroides/administração & dosagem , Anestésicos Locais/administração & dosagem , Artralgia/tratamento farmacológico , Medição da Dor/estatística & dados numéricos , Radiografia Intervencionista/estatística & dados numéricos , Síndrome de Colisão do Ombro/tratamento farmacológico , Síndrome de Colisão do Ombro/epidemiologia , Acrômio , Artralgia/diagnóstico por imagem , Feminino , Humanos , Injeções Intra-Articulares , Masculino , Pessoa de Meia-Idade , Prevalência , Punções/métodos , Síndrome de Colisão do Ombro/diagnóstico por imagem , Suíça/epidemiologia , Resultado do Tratamento
10.
Eur Spine J ; 22 Suppl 3: S466-70, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23328873

RESUMO

We report two detrimental neurologic complications after technically correct selected cervical nerve root blocks. Based on these cases and a thorough review of the literature, the indication for cervical nerve root blocks was reconsidered and limited. Similarly, we modified our technique to further reduce the likelihood for the occurrence of such severe complications.


Assuntos
Anestésicos Locais/efeitos adversos , Injeções Intra-Articulares/efeitos adversos , Bloqueio Nervoso/efeitos adversos , Isquemia do Cordão Espinal/etiologia , Raízes Nervosas Espinhais/efeitos dos fármacos , Idoso , Vértebras Cervicais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Bloqueio Nervoso/métodos
11.
Skeletal Radiol ; 42(3): 419-29, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22926680

RESUMO

OBJECTIVE: To determine the optimal intra-articular iodine concentration for C-arm flat-panel computed tomography (FPCT) arthrography using advanced joint phantoms and to evaluate its application in human cadaveric wrists and elbows. Multi-detector (MD) CT served as the standard of reference. MATERIALS AND METHODS: Joint phantoms and 10 human cadaveric wrist and elbow joints were scanned with C-arm FPCT (5-s, 8-s, and 20-s runs) and standard MDCT using different and optimal concentrations of iodinated contrast material. CT numbers of contrast material, tissue, and noise were measured and contrast-to-noise ratios (CNR) calculated for quantitative analysis. Image and depiction of cartilage, bone, and soft tissues were rated. Radiation doses were compared. RESULTS: In FPCT, iodine concentrations positively correlated with CT numbers and noise of contrast material and with radiation dose (r = 0.713-0.996, p < 0.05 each). At an iodine concentration of 45 mg/ml, CNR of cartilage and soft tissues were highest for all FPCT acquisitions and higher than in MDCT. The 20-s FPCT run performed best for image quality and depiction of anatomical structures and was rated overall equal to MDCT (p = 0.857). CONCLUSION: The optimal iodine concentration for C-arm FPCT arthrography in this study is 45 mg/ml, leading to superior CNR and image quality for an optimal FPCT protocol compared with standard MDCT arthrography in human cadaveric joints.


Assuntos
Artrografia/instrumentação , Articulação do Cotovelo/diagnóstico por imagem , Iohexol/análogos & derivados , Tomografia Computadorizada por Raios X/instrumentação , Articulação do Punho/diagnóstico por imagem , Ecrans Intensificadores para Raios X , Artrografia/métodos , Cadáver , Meios de Contraste/administração & dosagem , Relação Dose-Resposta a Droga , Desenho de Equipamento , Análise de Falha de Equipamento , Feminino , Humanos , Iohexol/administração & dosagem , Masculino , Projetos Piloto , Intensificação de Imagem Radiográfica/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Tomografia Computadorizada por Raios X/métodos
12.
J Manipulative Physiol Ther ; 36(4): 218-25, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23706678

RESUMO

OBJECTIVES: The purpose of this study was to compare self-reported pain and "improvement" of patients with symptomatic, magnetic resonance imaging-confirmed, lumbar disk herniations treated with either high-velocity, low-amplitude spinal manipulative therapy (SMT) or nerve root injections (NRI). METHODS: This prospective cohort comparative effectiveness study included 102 age- and sex-matched patients treated with either NRI or SMT. Numerical rating scale (NRS) pain data were collected before treatment. One month after treatment, current NRS pain levels and overall improvement assessed using the Patient Global Impression of Change scale were recorded. The proportion of patients, "improved" or "worse," was calculated for each treatment. Comparison of pretreatment and 1-month NRS scores used the paired t test. Numerical rating scale and NRS change scores for the 2 groups were compared using the unpaired t test. The groups were also compared for "improvement" using the χ(2) test. Odds ratios with 95% confidence intervals were calculated. Average direct procedure costs for each treatment were calculated. RESULTS: No significant differences for self-reported pain or improvement were found between the 2 groups. "Improvement" was reported in 76.5% of SMT patients and in 62.7% of the NRI group. Both groups reported significantly reduced NRS scores at 1 month (P = .0001). Average cost for treatment with SMT was Swiss Francs 533.77 (US $558.75) and Swiss Francs 697 (US $729.61) for NRI. CONCLUSIONS: Most SMT and NRI patients with radicular low back pain and magnetic resonance imaging-confirmed disk herniation matching symptomatic presentation reported significant and clinically relevant reduction in self-reported pain level and increased global perception of improvement. There were no significant differences in outcomes between NRI and SMT. When considering direct procedure costs, the average cost of SMT was slightly less expensive.


Assuntos
Deslocamento do Disco Intervertebral/diagnóstico , Deslocamento do Disco Intervertebral/terapia , Vértebras Lombares/patologia , Imageamento por Ressonância Magnética/métodos , Manipulação da Coluna/métodos , Raízes Nervosas Espinhais/efeitos dos fármacos , Adulto , Idoso , Analgésicos/uso terapêutico , Estudos de Casos e Controles , Estudos de Coortes , Análise Custo-Benefício , Feminino , Seguimentos , Humanos , Injeções Epidurais/economia , Injeções Epidurais/métodos , Dor Lombar/diagnóstico , Dor Lombar/etiologia , Vértebras Lombares/efeitos dos fármacos , Masculino , Manipulação da Coluna/economia , Pessoa de Meia-Idade , Medição da Dor , Posicionamento do Paciente , Satisfação do Paciente , Estudos Prospectivos , Medição de Risco , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do Tratamento
13.
Radiology ; 264(1): 174-9, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22550311

RESUMO

PURPOSE: To develop a list of radiologic criteria for describing lumbar spinal stenosis, to learn from experts which parameters they consider to be most important, and to assess the strength of agreement among experts on the most relevant criteria. MATERIALS AND METHODS: An expert panel of 41 radiologists (musculoskeletal experts and neuroradiologists from Europe and the United States) was formed. A three-round Delphi survey was conducted. Twenty-seven of the 41 nominated experts agreed to participate; 21 completed all three rounds. In the first round, experts were asked to complete a list of suggested parameters and cutoff values to describe lumbar spinal stenosis. In the second round, panelists rated the diagnostic relevance of each parameter (visual analog scale, 0-10). In the third round, panelists were provided with the group results (median and range) and their own answers and had the opportunity to adapt their judgments from round 2. To assess the degree of consensus among experts, the Cronbach α was calculated. RESULTS: The qualitative criteria disk protrusion and perineural intraforaminal fat were rated as the most important diagnostic indicators, with median scores of 9 (range, 2-10). The highest rated quantitative criterion was the anteroposterior diameter of the osseous canal, with a median score of 8; however, there was a wide range of scores (range, 0-10). The median Cronbach α of all panelists within the group was 0.81 after the third round. CONCLUSION: Results of the survey suggest that there are no broadly accepted quantitative criteria and only partially accepted qualitative criteria for the diagnosis of lumbar spinal stenosis. The latter include disk protrusion, lack of perineural intraforaminal fat, hypertrophic facet joint degeneration, absent fluid around the cauda equine, and hypertrophy of the ligamentum flavum.


Assuntos
Técnica Delphi , Diagnóstico por Imagem , Vértebras Lombares , Estenose Espinal/diagnóstico , Humanos
14.
Radiology ; 264(1): 164-73, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22570505

RESUMO

PURPOSE: To evaluate prospectively the performance of noncalcium images reconstructed from dual-energy (DE) computed tomography (CT) for the diagnosis of bone marrow lesions in patients with acute ankle joint trauma in comparison with magnetic resonance (MR) images. MATERIALS AND METHODS: The study had local ethics board approval, and written informed consent was obtained. Thirty consecutive patients (15 women; mean age, 34 years±11.8 [standard deviation]) underwent dual-source DE CT (80 kVp and 140 kVp with tin filter) and MR imaging within 1 day following acute ankle trauma. DE CT data were postprocessed by using a three-material decomposition algorithm for generating noncalcium images. MR and noncalcium images were graded by two blinded, independent readers using a four-point system (1=distinct bone marrow lesion, 4=no lesion); CT numbers in noncalcium images were calculated by a third reader. MR imaging interpretations served as the reference standard. RESULTS: Interreader agreement for qualitative grading of DE CT images was substantial (κ=0.66). The respective sensitivity, specificity, positive predictive value, and negative predictive value of DE CT for depicting distinct bone marrow lesions for both readers were 90.0% each, 80.5% and 81.6%, 25.4% and 26.5%, and 99.1% each. In regions without abnormality, CT numbers in noncalcium images gradually increased from proximal to distal location (P<.001). Significant differences in CT numbers were found in regions positive for bone marrow lesions compared with those that were negative (P<.001). CT numbers for the diagnosis of distinct bone marrow lesions according to MR imaging revealed areas under the receiver operating characteristic curve of 0.973, 0.813, and 0.758 for ankle mortise, talar dome, and talar body/head, respectively. CONCLUSION: Compared with MR images, distinct traumatic bone marrow lesions of the ankle joint can be diagnosed on noncalcium images reconstructed from DE CT with high sensitivity and excellent negative predictive value, but with moderate specificity and low positive predictive value.


Assuntos
Traumatismos do Tornozelo/patologia , Medula Óssea/patologia , Imageamento por Ressonância Magnética/métodos , Tomografia Computadorizada por Raios X/métodos , Adulto , Algoritmos , Feminino , Humanos , Interpretação de Imagem Assistida por Computador , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Curva ROC , Sensibilidade e Especificidade
15.
NMR Biomed ; 25(8): 1007-14, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22311278

RESUMO

The aim of this study was to quantitatively assess the field strength dependence of the transverse relaxation rate (R(2) *) change in cortical gray matter induced by hyperoxia and hyperoxic hypercapnia versus normoxia in an intra-individual comparison of young healthy volunteers. Medical air (21% O(2) ), pure oxygen and carbogen (95% O(2) , 5% CO(2) ) were alternatively administered in a block-design temporal pattern to induce normoxia, hyperoxia and hyperoxic hypercapnia, respectively. Local R(2) * values were determined from three-dimensional, multiple, radiofrequency-spoiled, fast field echo data acquired at 1.5, 3 and 7 T. Image quality was good at all field strengths. Under normoxia, the mean gray matter R(2) * values were 13.3 ± 2.7 s(-1) (1.5 T), 16.9 ± 0.9 s(-1) (3 T) and 29.0 ± 2.6 s(-1) (7 T). Both hyperoxic gases induced relaxation rate decreases ΔR(2) *, whose magnitudes increased quadratically with the field strength [carbogen: -0.69 ± 0.20 s(-1) (1.5 T), -1.49 ± 0.49 s(-1) (3 T), -5.64 ± 0.67 s(-1) (7 T); oxygen: -0.39 ± 0.20 s(-1) (1.5 T), -0.78 ± 0.48 s(-1) (3 T), -3.86 ± 1.00 s(-1) (7 T)]. Carbogen produced larger R(2) * changes than oxygen at all field strengths. The relative change ΔR(2) */R(2) * also increased with the field strength with a power between 1 and 2 for both carbogen and oxygen. The statistical significance of the R(2) * response improved with increasing B(0) and was higher for carbogen than for oxygen. For a sequence with pure T(2) * weighting of the signal response to respiratory challenge, the results suggested a maximum carbogen-induced signal difference of 19.3% of the baseline signal at 7 T and TE = 38 ms, but a maximum oxygen-induced signal difference of only 3.0% at 1.5 T and TE = 76 ms. For 3 T, maximum signal changes of 4.7% (oxygen) and 8.9% (carbogen) were computed. In conclusion, the R(2) * response to hyperoxic respiratory challenge was stronger for carbogen than for oxygen, and increased quadratically with the static magnetic field strength for both challenges, which highlights the importance of high field strengths for future studies aimed at probing oxygen physiology in clinical settings.


Assuntos
Córtex Cerebral/metabolismo , Hiperóxia/metabolismo , Ressonância Magnética Nuclear Biomolecular/métodos , Oxigênio/metabolismo , Respiração , Processamento de Sinais Assistido por Computador , Adulto , Feminino , Saúde , Humanos , Masculino , Oxigênio/sangue , Fatores de Tempo
16.
J Magn Reson Imaging ; 36(6): 1413-20, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22865713

RESUMO

PURPOSE: To investigate the role of the cervical spine muscles in whiplash injury. We hypothesized that (i) cervical muscle hypotrophy would be evident after a 6-month follow-up and, (ii) cervical muscle hypotrophy would correlate with symptom persistence probably related to pain or inactivity. MATERIALS AND METHODS: Ninety symptomatic patients (48 females) were recruited from our emergency department and examined within 48 h, and at 3, and 6 months after a motor vehicle accident. MRI cross-sectional muscle area (CSA) measurements were performed bilaterally of the cervical extensor and sternocleidomastoid muscles using transverse STIR (Short Tau inversion Recovery) sequences at the C2 (deep and total dorsal cervical extensor muscles), C4 (sternocleidomastoid muscles) and C5 (deep and total dorsal cervical extensor muscles) levels. Two blinded raters independently performed the measurements at each time point. First, CSA changes over time were analyzed and, second, CSAs were correlated with clinical outcomes (EuroQuol, Whiplash Disability Score, neck pain intensity [VAS], cervical spine mobility). RESULTS: There was a high agreement of CSA measurements between the two raters. Women consistently had smaller CSAs than men. There were no significant changes of CSAs over time at any of the three levels. There were no consistent significant correlations of CSA values with the clinical scores at all time points except with the body mass index. CONCLUSION: Our results do not support a major role of cervical muscle volume in the genesis of symptoms after whiplash injury.


Assuntos
Interpretação de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Atrofia Muscular/etiologia , Atrofia Muscular/patologia , Músculos do Pescoço/patologia , Traumatismos em Chicotada/complicações , Traumatismos em Chicotada/patologia , Adulto , Anatomia Transversal/métodos , Vértebras Cervicais/patologia , Feminino , Seguimentos , Humanos , Aumento da Imagem/métodos , Masculino , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
17.
Skeletal Radiol ; 41(6): 699-705, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21946953

RESUMO

OBJECTIVE: To describe a posterolateral fluoroscopy-guided injection technique into the posterior subtalar joint and to report patient outcomes 1 month post-injection. MATERIALS AND METHODS: Twenty-three consecutive adult patients who underwent fluoroscopy-guided injection into the posterior subtalar joint using a direct posterolateral approach and who returned an outcomes-based postal questionnaire after receiving this injection were included. Numerical pain rating scale (NRS) data were collected prior to injection. NRS and Patient's Global Impression of Change (PGIC) scales were completed 1 day, 1 week, and 1 month after injection. The proportion of patients who improved was calculated for each time period. Baseline NRS data were compared to each time point using the Wilcoxon test to assess differences. Spearman's correlation coefficient was used to compare the 20 min NRS score with all follow-up NRS scores. All available images were reviewed for the presence of subtalar osteoarthritis (OA). Patient charts were reviewed to identify characteristics of patients referred for subtalar injections. Risk ratios were calculated comparing presence of OA or other abnormalities with improvement. RESULTS: A posterolateral approach for fluoroscopy-guided injections into the subtalar joint is described. There was a significant reduction in the mean NRS score at all time periods compared to baseline (p ≤ 0.004). One-third of patients (7/21) reported clinically relevant improvement at 1 month. CONCLUSIONS: Fluoroscopy-guided puncture of the posterior subtalar joint using a posterolateral approach is possible. Clinically significant improvement is reported in 33% of patients after 1 month.


Assuntos
Anestésicos Locais/administração & dosagem , Artralgia/diagnóstico por imagem , Artralgia/tratamento farmacológico , Artrografia/métodos , Fluoroscopia/métodos , Radiografia Intervencionista/métodos , Articulação Talocalcânea/diagnóstico por imagem , Adulto , Idoso , Feminino , Humanos , Injeções Intra-Arteriais/métodos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Articulação Talocalcânea/efeitos dos fármacos , Resultado do Tratamento
18.
J Magn Reson Imaging ; 34(5): 1007-21, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22002752

RESUMO

Advances in orthopedic and arthroscopic surgical procedures of the knee such as, knee replacement, ligamentous reconstruction as well as articular cartilage and meniscus repair techniques have resulted in a significant increase in the number of patients undergoing knee arthroscopy or open surgery. As a consequence postoperative MR imaging examinations increase. Comprehensive knowledge of the normal postoperative MR imaging appearances and abnormal findings in the knee associated with failure or complications of common orthopedic and arthroscopic surgical procedures currently undertaken is crucial. This article reviews the various normal and pathological postoperative MR imaging findings following anterior and posterior cruciate ligament, medial collateral ligament and posterolateral corner reconstruction, meniscus and articular cartilage surgery as well as total knee arthroplasty with emphasis on those surgical procedures which general radiologists will likely be faced in their daily clinical routine.


Assuntos
Joelho/cirurgia , Imageamento por Ressonância Magnética/métodos , Adolescente , Adulto , Idoso , Ligamento Cruzado Anterior/patologia , Artroscopia/métodos , Cartilagem/patologia , Feminino , Humanos , Ligamentos/patologia , Masculino , Pessoa de Meia-Idade , Ortopedia/métodos , Período Pós-Operatório , Recidiva , Resultado do Tratamento
19.
J Magn Reson Imaging ; 33(3): 661-7, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21563250

RESUMO

PURPOSE: To evaluate in vivo MR imaging of the wrist at 3.0 Tesla (T) and 7.0T quantitatively and qualitatively. MATERIALS AND METHODS: To enable unbiased signal-to-noise ratio (SNR) comparisons, geometrically identical eight-channel receiver arrays were used at both field strengths. First, in vitro images of a phantom bottle were acquired at 3.0T and 7.0T to obtain an estimate of the maximum SNR gain that can be expected. MR images of the dominant wrist of 10 healthy volunteers were acquired at both field strengths. All measurements were done using the same sequence parameters. Quantitative SNR maps were calculated on a pixel-by-pixel basis and analyzed in several regions-of-interest. Furthermore, the images were qualitatively evaluated by two independent radiologists. RESULTS: The quantitative analysis showed SNR increases of up to 100% at 7.0T compared with 3.0T, with considerable variation between different anatomical structures. The qualitative analysis revealed no significant difference in the visualization of anatomical structures comparing 3.0T and 7.0T MR images (P>0.05). CONCLUSION: The presented results establish the SNR benefits of the transition from 3.0T to 7.0T for wrist imaging without bias by different array designs and based on exact, algebraic SNR quantification. The observed SNR increase nearly reaches expected values but varies greatly between different tissues. It does not necessarily improve the visibility of anatomic structures but adds valuable latitude for sequence optimization.


Assuntos
Imageamento por Ressonância Magnética/métodos , Articulação do Punho/patologia , Adulto , Artefatos , Cartilagem Articular/patologia , Desenho de Equipamento , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Técnicas In Vitro , Masculino , Pessoa de Meia-Idade , Modelos Estatísticos , Imagens de Fantasmas , Punho/patologia
20.
J Magn Reson Imaging ; 33(3): 668-75, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21563251

RESUMO

PURPOSE: To quantitatively compare the muscle cross-sectional areas (CSAs) of the cervical muscles in symptomatic acute whiplash patients versus healthy controls. We hypothesized, that symptomatic whiplash patients have smaller cervical muscle CSAs than matched controls and that smaller cervical muscle CSAs in women might explain that women more frequently are symptomatic after whiplash injury than men. MATERIALS AND METHODS: Prospective controlled study. Thirty-eight consecutive acute whiplash patients were examined within 48 h after a motor vehicle accident and 38 healthy age- and sex-matched controls, each half female, half male, were examined with the same protocol. MRI CSA measurements were performed of the deep and total cervical extensor muscles as well as the sternocleidomastoid muscles using transversal STIR (Short T1 Inversion Recovery) sequences on level C2, C4, and C5 by two blinded raters. Clinical symptoms were assessed with patient questionnaires (EuroQuol 5D, Specific Whiplash Questionnaire, head- and neck pain intensity [VAS]). RESULTS: Agreement of measurements between the two raters was high (intraclass correlation 0.52 to 0.85 for the different levels). No significant difference in age and body mass index were seen between patients and controls and the distribution of genders across groups was identical. There were no significant differences between patients and controls for all CSAs. Women had consistently smaller CSAs than men. The CSAs showed no significant correlation with the pain intensity of neck pain and headache but a consistent tendency of less neck pain and more headache with greater CSAs. CONCLUSION: This small study provides no evidence that subjects with smaller CSAs of cervical extensor muscles have a higher risk in developing symptoms after a whiplash injury and confirms smaller CSA in women.


Assuntos
Imageamento por Ressonância Magnética/métodos , Traumatismos em Chicotada/diagnóstico , Acidentes de Trânsito , Adulto , Índice de Massa Corporal , Estudos de Casos e Controles , Vértebras Cervicais/patologia , Feminino , Humanos , Masculino , Modelos Estatísticos , Músculos/patologia , Dor , Estudos Prospectivos , Inquéritos e Questionários
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