Detalhe da pesquisa
1.
Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
Chemistry
; 30(7): e202302909, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37910861
2.
Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus.
Mar Drugs
; 22(3)2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38535458
3.
Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation.
Pharmacol Res
; 190: 106715, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868367
4.
Expression of α3ß2ß4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists.
J Neurochem
; 154(2): 158-176, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31967330
5.
Opioid system influences gut-brain axis: Dysbiosis and related alterations.
Pharmacol Res
; 159: 104928, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504837
6.
Molecular determinants of α-conotoxin potency for inhibition of human and rat α6ß4 nicotinic acetylcholine receptors.
J Biol Chem
; 293(46): 17838-17852, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249616
7.
Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells.
J Neurochem
; 140(1): 37-52, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27805736
8.
α-Conotoxins Identify the α3ß4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells.
Mol Pharmacol
; 88(5): 881-93, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26330550
9.
Positional scanning mutagenesis of α-conotoxin PeIA identifies critical residues that confer potency and selectivity for α6/α3ß2ß3 and α3ß2 nicotinic acetylcholine receptors.
J Biol Chem
; 288(35): 25428-25439, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23846688
10.
Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
J Med Chem
; 67(11): 9587-9598, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38814877
11.
Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of α6-Nicotinic Receptors and Dopamine Transporters.
ACS Chem Neurosci
; 15(9): 1738-1754, 2024 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38613458
12.
Nicotinic acetylcholine receptors in dorsal root ganglion neurons include the α6ß4* subtype.
FASEB J
; 26(2): 917-26, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22024738
13.
α-Conotoxin PeIA[S9H,V10A,E14N] potently and selectively blocks α6ß2ß3 versus α6ß4 nicotinic acetylcholine receptors.
Mol Pharmacol
; 82(5): 972-82, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22914547
14.
Alkaloid ligands enable function of homomeric human α10 nicotinic acetylcholine receptors.
Front Pharmacol
; 13: 981760, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36188578
15.
Nicotinic Acetylcholine Receptor Involvement in Inflammatory Bowel Disease and Interactions with Gut Microbiota.
Int J Environ Res Public Health
; 18(3)2021 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33572734
16.
Computational and Functional Mapping of Human and Rat α6ß4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.
J Med Chem
; 64(3): 1685-1700, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33523678
17.
Therapeutic concentrations of varenicline increases exocytotic release of catecholamines from human and rat adrenal chromaffin cells in the presence of nicotine.
Neuropharmacology
; 195: 108632, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097947
18.
Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling alpha 7 nicotinic acetylcholine receptors.
J Neurochem
; 114(4): 994-1006, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20492354
19.
A novel fluorescent alpha-conotoxin for the study of alpha7 nicotinic acetylcholine receptors.
J Neurochem
; 111(1): 80-9, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19650873
20.
PeIA-5466: A Novel Peptide Antagonist Containing Non-natural Amino Acids That Selectively Targets α3ß2 Nicotinic Acetylcholine Receptors.
J Med Chem
; 62(13): 6262-6275, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31194549