1.
J Oncol Pharm Pract
; 26(1): 212-215, 2020 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30854923
RESUMO
We report a case of acute myeloid leukemia with complex cytogenetic abnormalities suggestive of preexisting myelodysplastic syndrome in a patient with habitual ingestion of colloidal silver as nutritional supplement for over 10 years and the medical literature is reviewed.
Assuntos
Aberrações Cromossômicas/induzido quimicamente , Leucemia Mieloide Aguda/induzido quimicamente , Prata/efeitos adversos , Idoso , Suplementos Nutricionais/efeitos adversos , Humanos , Leucemia Mieloide Aguda/genética , Masculino
2.
J Oncol Pharm Pract
; 22(3): 548-51, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25791511
RESUMO
Pharmacogenetics is a study of how genetic variation of an individual affects the drug response. We report a case of recurrent pancytopenia resulting from maintenance chemotherapy in a patient with acute promyelocytic leukemia and two pharmacogenetic mutations, namely, methylene tetrahydrofolate reductase C677T homozygous mutation and thiopurine methyltransferase mutation.