Detalhe da pesquisa
1.
E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Nat Immunol
; 24(12): 2021-2031, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37903858
2.
TLR8 Is a Sensor of RNase T2 Degradation Products.
Cell
; 179(6): 1264-1275.e13, 2019 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31778653
3.
Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.
Immunity
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697119
4.
Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production.
Immunity
; 57(3): 446-461.e7, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423012
5.
Molecular mechanisms and cellular functions of cGAS-STING signalling.
Nat Rev Mol Cell Biol
; 21(9): 501-521, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424334
6.
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Cell
; 171(5): 1110-1124.e18, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033128
7.
IKKß primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Immunity
; 55(12): 2271-2284.e7, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36384135
8.
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
Immunity
; 54(4): 648-659.e8, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667383
9.
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
Nature
; 609(7927): 590-596, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002575
10.
Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages.
EMBO J
; 42(23): e113279, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37881155
11.
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.
Nat Immunol
; 16(10): 1025-33, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26343537
12.
Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Nature
; 587(7835): 678-682, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911480
13.
Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses.
Nat Methods
; 19(1): 81-89, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34949807
14.
Recognition of Endogenous Nucleic Acids by the Innate Immune System.
Immunity
; 44(4): 739-54, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27096317
15.
Inflammasome-Dependent Induction of Adaptive NK Cell Memory.
Immunity
; 44(6): 1406-21, 2016 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287410
16.
Human Monocytes Engage an Alternative Inflammasome Pathway.
Immunity
; 44(4): 833-46, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27037191
17.
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
PLoS Biol
; 20(11): e3001351, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342970
18.
STING agonism turns human T cells into interferon-producing cells but impedes their functionality.
EMBO Rep
; 24(3): e55536, 2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36705069
19.
CARD8 inflammasome activation triggers pyroptosis in human T cells.
EMBO J
; 39(19): e105071, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32840892
20.
A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.
Immunity
; 43(1): 41-51, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26187414