Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness.

Gyimesi, Máté; Horváth, Ádám I; Túrós, Demeter; Suthar, Sharad Kumar; Pénzes, Máté; Kurdi, Csilla; Canon, Louise; Kikuti, Carlos; Ruppel, Kathleen M; Trivedi, Darshan V; Spudich, James A; Lorincz, István; Rauscher, Anna Á; Kovács, Mihály; Pál, Endre; Komoly, Sámuel; Houdusse, Anne; Málnási-Csizmadia, András.

Cell ; 183(2): 335-346.e13, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33035452

2.

A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis.

Blanc, Florian E C; Houdusse, Anne; Cecchini, Marco.

PLoS Comput Biol ; 20(4): e1012005, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38662764

3.

Myosin VI rewrites the rules for myosin motors.

Sweeney, H Lee; Houdusse, Anne.

Cell ; 141(4): 573-82, 2010 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-20478251

4.

Dynein swings into action.

Houdusse, Anne; Carter, Andrew P.

Cell ; 136(3): 395-6, 2009 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-19203573

5.

Force Generation by Myosin Motors: A Structural Perspective.

Robert-Paganin, Julien; Pylypenko, Olena; Kikuti, Carlos; Sweeney, H Lee; Houdusse, Anne.

Chem Rev ; 120(1): 5-35, 2020 01 08.

Artigo em Inglês | MEDLINE | ID: mdl-31689091

6.

Optimized filopodia formation requires myosin tail domain cooperation.

Arthur, Ashley L; Songster, Livia D; Sirkia, Helena; Bhattacharya, Akash; Kikuti, Carlos; Borrega, Fernanda Pires; Houdusse, Anne; Titus, Margaret A.

Proc Natl Acad Sci U S A ; 116(44): 22196-22204, 2019 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-31611382

7.

An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics.

Blanc, Florian; Isabet, Tatiana; Benisty, Hannah; Sweeney, H Lee; Cecchini, Marco; Houdusse, Anne.

Proc Natl Acad Sci U S A ; 115(24): 6213-6218, 2018 06 12.

Artigo em Inglês | MEDLINE | ID: mdl-29844196

8.

How Myosin Generates Force on Actin Filaments.

Houdusse, Anne; Sweeney, H Lee.

Trends Biochem Sci ; 41(12): 989-997, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27717739

9.

Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI.

Ménétrey, Julie; Isabet, Tatiana; Ropars, Virginie; Mukherjea, Monalisa; Pylypenko, Olena; Liu, Xiaoyan; Perez, Javier; Vachette, Patrice; Sweeney, H Lee; Houdusse, Anne M.

Mol Cell ; 48(1): 75-86, 2012 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-22940248

10.

Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins.

Liu, Judy S; Schubert, Christian R; Fu, Xiaoqin; Fourniol, Franck J; Jaiswal, Jyoti K; Houdusse, Anne; Stultz, Collin M; Moores, Carolyn A; Walsh, Christopher A.

Mol Cell ; 47(5): 707-21, 2012 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-22857951

11.

Myosin Structures.

Sweeney, H Lee; Houdusse, Anne; Robert-Paganin, Julien.

Adv Exp Med Biol ; 1239: 7-19, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32451853

12.

Emerging roles of MICAL family proteins - from actin oxidation to membrane trafficking during cytokinesis.

Frémont, Stéphane; Romet-Lemonne, Guillaume; Houdusse, Anne; Echard, Arnaud.

J Cell Sci ; 130(9): 1509-1517, 2017 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-28373242

13.

2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology.

Lucchino, Marco; Billet, Anne; Versini, Antoine; Bavireddi, Harikrishna; Dasari, Bhanu-Das; Debieu, Sylvain; Colombeau, Ludovic; Cañeque, Tatiana; Wagner, Alain; Masson, Géraldine; Taran, Frédéric; Karoyan, Philippe; Delepierre, Muriel; Gaillet, Christine; Houdusse, Anne; Britton, Sébastien; Schmidt, Frédéric; Florent, Jean-Claude; Belmont, Philippe; Monchaud, David; Cossy, Janine; Thomas, Christophe; Gautier, Arnaud; Johannes, Ludger; Rodriguez, Raphaël.

Chembiochem ; 20(7): 968-973, 2019 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-30803119

14.

MyTH4-FERM myosins have an ancient and conserved role in filopod formation.

Petersen, Karl J; Goodson, Holly V; Arthur, Ashley L; Luxton, G W Gant; Houdusse, Anne; Titus, Margaret A.

Proc Natl Acad Sci U S A ; 113(50): E8059-E8068, 2016 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-27911821

15.

Force-producing ADP state of myosin bound to actin.

Wulf, Sarah F; Ropars, Virginie; Fujita-Becker, Setsuko; Oster, Marco; Hofhaus, Goetz; Trabuco, Leonardo G; Pylypenko, Olena; Sweeney, H Lee; Houdusse, Anne M; Schröder, Rasmus R.

Proc Natl Acad Sci U S A ; 113(13): E1844-52, 2016 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-26976594

16.

Myosin MyTH4-FERM structures highlight important principles of convergent evolution.

Planelles-Herrero, Vicente José; Blanc, Florian; Sirigu, Serena; Sirkia, Helena; Clause, Jeffrey; Sourigues, Yannick; Johnsrud, Daniel O; Amigues, Beatrice; Cecchini, Marco; Gilbert, Susan P; Houdusse, Anne; Titus, Margaret A.

Proc Natl Acad Sci U S A ; 113(21): E2906-15, 2016 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-27166421

17.

Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.

Sirigu, Serena; Hartman, James J; Planelles-Herrero, Vicente José; Ropars, Virginie; Clancy, Sheila; Wang, Xi; Chuang, Grace; Qian, Xiangping; Lu, Pu-Ping; Barrett, Edward; Rudolph, Karin; Royer, Christopher; Morgan, Bradley P; Stura, Enrico A; Malik, Fady I; Houdusse, Anne M.

Proc Natl Acad Sci U S A ; 113(47): E7448-E7455, 2016 11 22.

Artigo em Inglês | MEDLINE | ID: mdl-27815532

18.

MYO5B, STX3, and STXBP2 mutations reveal a common disease mechanism that unifies a subset of congenital diarrheal disorders: A mutation update.

Dhekne, Herschel S; Pylypenko, Olena; Overeem, Arend W; Zibouche, Malik; Ferreira, Rosaria J; van der Velde, K Joeri; Rings, Edmond H H M; Posovszky, Carsten; van der Sluijs, Peter; Swertz, Morris A; Houdusse, Anne; van IJzendoorn, Sven C D.

Hum Mutat ; 39(3): 333-344, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29266534

19.

Myosin VI deafness mutation prevents the initiation of processive runs on actin.

Pylypenko, Olena; Song, Lin; Shima, Ai; Yang, Zhaohui; Houdusse, Anne M; Sweeney, H Lee.

Proc Natl Acad Sci U S A ; 112(11): E1201-9, 2015 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-25751888

20.

Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach.

Mukherjea, Monalisa; Llinas, Paola; Kim, HyeongJun; Travaglia, Mirko; Safer, Daniel; Ménétrey, Julie; Franzini-Armstrong, Clara; Selvin, Paul R; Houdusse, Anne; Sweeney, H Lee.

Mol Cell ; 35(3): 305-15, 2009 Aug 14.

Artigo em Inglês | MEDLINE | ID: mdl-19664948

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