Detalhe da pesquisa
1.
Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.
Mol Psychiatry
; 27(3): 1805-1815, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165396
2.
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Proc Natl Acad Sci U S A
; 116(27): 13320-13329, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209056
3.
Creating a potential diagnostic for prostate cancer risk stratification (InformMDx™) by translating novel scientific discoveries concerning cAMP degrading phosphodiesterase-4D7 (PDE4D7).
Clin Sci (Lond)
; 133(2): 269-286, 2019 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683712
4.
Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α.
Mol Cell
; 44(3): 476-90, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055192
5.
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.
Mol Cell
; 42(1): 84-95, 2011 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21474070
6.
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection.
Circulation
; 146(23): 1779-1782, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36469592
7.
Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners.
Biochem J
; 474(4): 597-609, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27993970
8.
Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.
J Neurosci
; 36(34): 8936-46, 2016 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559174
9.
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.
Nature
; 473(7345): 92-6, 2011 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21471969
10.
Withdrawal: Mdm2 directs the ubiquitination of ß-arrestin-sequestered cAMP phosphodiesterase-4D5.
J Biol Chem
; 295(34): 12328, 2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826336
11.
Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms.
Proc Natl Acad Sci U S A
; 110(49): 19778-83, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24248367
12.
Phosphodiesterase-8A binds to and regulates Raf-1 kinase.
Proc Natl Acad Sci U S A
; 110(16): E1533-42, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23509299
13.
PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding.
Biochim Biophys Acta
; 1843(11): 2765-74, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25110345
14.
Sleep deprivation impairs cAMP signalling in the hippocampus.
Nature
; 461(7267): 1122-5, 2009 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19847264
15.
Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown.
Trends Biochem Sci
; 35(2): 91-100, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19864144
16.
Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function.
J Cell Sci
; 124(Pt 13): 2253-66, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21652625
17.
Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.
Proc Natl Acad Sci U S A
; 107(18): 8457-62, 2010 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20404172
18.
A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.
J Biol Chem
; 286(18): 16285-96, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393242
19.
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
J Biol Chem
; 286(11): 9079-96, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177871
20.
Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes.
Curr Opin Cell Biol
; 17(2): 129-34, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15780588