Detalhe da pesquisa
1.
Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and exhibits a high barrier to the development of resistance.
Antimicrob Agents Chemother
; 68(1): e0095323, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047645
2.
Selective small-molecule inhibition of an RNA structural element.
Nature
; 526(7575): 672-7, 2015 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416753
3.
Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch.
RNA Biol
; 13(10): 946-954, 2016 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27485612
4.
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
J Med Chem
; 67(5): 3935-3958, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365209
5.
Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3.
J Hepatol
; 59(1): 31-7, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23454058
6.
Boceprevir with peginterferon alfa-2a-ribavirin is effective for previously treated chronic hepatitis C genotype 1 infection.
Clin Gastroenterol Hepatol
; 11(1): 81-87.e4; quiz e5, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23064222
7.
First insights into the biodiversity and biogeography of the Southern Ocean deep sea.
Nature
; 447(7142): 307-11, 2007 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17507981
8.
Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Commun Biol
; 6(1): 649, 2023 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37337079
9.
Structure-function analysis of human immunodeficiency virus type 1 gp120 amino acid mutations associated with resistance to the CCR5 coreceptor antagonist vicriviroc.
J Virol
; 83(23): 12151-63, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19776131
10.
Screening for antiviral inhibitors of the HIV integrase-LEDGF/p75 interaction using the AlphaScreen luminescent proximity assay.
J Biomol Screen
; 13(5): 406-14, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18480474
11.
Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-Molecule Ligand of the Flavin Mononucleotide Riboswitch.
Methods Mol Biol
; 1787: 19-40, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29736707
12.
Deposition of artificial radionuclides in sediments of Loch Etive, Scotland.
J Environ Radioact
; 187: 45-52, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29429873
13.
Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
ACS Chem Biol
; 13(3): 820-831, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29412640
14.
Ecosystem uptake and transfer of Sellafield-derived radiocarbon (14C). Part 1. The Irish Sea.
Mar Pollut Bull
; 114(2): 792-804, 2017 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27839777
15.
Ecosystem uptake and transfer of Sellafield-derived radiocarbon (14C) part 2: The West of Scotland.
Mar Pollut Bull
; 115(1-2): 57-66, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899176
16.
Nuclear reprocessing-related radiocarbon (14C) uptake into UK marine mammals.
Mar Pollut Bull
; 124(1): 43-50, 2017 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28693808
17.
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol
; 24(5): 576-588.e6, 2017 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28434876
18.
Adenoviral-mediated expression of a kinase-dead mutant of Akt induces apoptosis selectively in tumor cells and suppresses tumor growth in mice.
Cancer Res
; 63(20): 6697-706, 2003 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14583464
19.
Pharmacologic indicators of antitumor efficacy for oncolytic virotherapy.
Cancer Res
; 63(14): 4003-8, 2003 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12873998
20.
Latest Quaternary palaeoceanographic change in the eastern North Atlantic based upon a dinoflagellate cyst event ecostratigraphy.
Heliyon
; 2(5): e00114, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27441285