Detalhe da pesquisa
1.
MC4R biased signalling and the conformational basis of biological function selections.
J Cell Mol Med
; 26(15): 4125-4136, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35818295
2.
Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma.
Bioconjug Chem
; 32(3): 497-501, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576604
3.
C-terminal modified Enkephalin-like tetrapeptides with enhanced affinities at the kappa opioid receptor and monoamine transporters.
Bioorg Med Chem
; 51: 116509, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34798381
4.
Aged Brains Express Less Melanocortin Receptors, Which Correlates with Age-Related Decline of Cognitive Functions.
Molecules
; 26(20)2021 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684847
5.
Development of N-Acetylated Dipalmitoyl-S-Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists.
Molecules
; 24(19)2019 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31569697
6.
Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages.
Circulation
; 136(1): 83-97, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450348
7.
Protection against ß-amyloid neurotoxicity by a non-toxic endogenous N-terminal ß-amyloid fragment and its active hexapeptide core sequence.
J Neurochem
; 144(2): 201-217, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29164616
8.
Structural Insights into Selective Ligand-Receptor Interactions Leading to Receptor Inactivation Utilizing Selective Melanocortin 3 Receptor Antagonists.
Biochemistry
; 56(32): 4201-4209, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28715181
9.
Synthesis and Investigation of Mixed µ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain.
J Heterocycl Chem
; 54(2): 1228-1235, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28819330
10.
Design of peptide and peptidomimetic ligands with novel pharmacological activity profiles.
Annu Rev Pharmacol Toxicol
; 53: 557-80, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23294313
11.
Design of cyclic peptides with biological activities from biologically active peptides: the case of peptide modulators of melanocortin receptors.
Biopolymers
; 106(6): 884-888, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486849
12.
Design of cyclized selective melanotropins.
Biopolymers
; 106(6): 876-883, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27561155
13.
Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5.
Mol Pharm
; 13(2): 534-44, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26713599
14.
Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.
Bioorg Med Chem Lett
; 26(1): 222-7, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611918
15.
Cyclic non-opioid dynorphin A analogues for the bradykinin receptors.
Bioorg Med Chem Lett
; 26(22): 5513-5516, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756562
16.
Design synthesis and structure-activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands.
Bioorg Med Chem
; 24(2): 85-91, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26712115
17.
Design, synthesis and biological evaluation of multifunctional ligands targeting opioid and bradykinin 2 receptors.
Bioorg Med Chem Lett
; 25(19): 4148-52, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26316468
18.
Modification of amphipathic non-opioid dynorphin A analogues for rat brain bradykinin receptors.
Bioorg Med Chem Lett
; 25(1): 30-3, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25434001
19.
Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities.
Bioorg Med Chem Lett
; 25(17): 3716-20, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26212775
20.
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives.
Bioorg Med Chem Lett
; 25(20): 4683-8, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26323872