Detalhe da pesquisa
1.
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Nature
; 626(8001): 1073-1083, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38355792
2.
Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.
EMBO J
; 42(17): e111719, 2023 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37431963
3.
An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.
EMBO J
; 41(23): e112338, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36254605
4.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Proc Natl Acad Sci U S A
; 119(49): e2123487119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454749
5.
Targeted mass spectrometry for monitoring of neural differentiation.
Biol Open
; 10(8)2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34357391
6.
Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.
Nat Commun
; 12(1): 3027, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021139
7.
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
EMBO Mol Med
; 13(9): e14745, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34309222
8.
Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.
Cell Rep
; 33(12): 108538, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33357437
9.
A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors.
Stem Cell Res Ther
; 10(1): 83, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867054
10.
Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells.
Nat Genet
; 51(12): 1691-1701, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740836
11.
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates.
Nat Neurosci
; 22(1): 65-77, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559480
12.
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.
Cell Rep
; 24(4): 987-1000.e7, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044993
13.
Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs.
Sci Transl Med
; 10(440)2018 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29743351
14.
Lentiviral-Mediated Transgenesis in Songbirds.
Methods Mol Biol
; 1650: 149-165, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28809019
15.
Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs.
Mol Ther Methods Clin Dev
; 3: 16046, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27462649
16.
New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases.
Swiss Med Wkly
; 145: w14192, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26376442
17.
Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.
Neuron
; 86(1): 218-32, 2015 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801706
18.
Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies.
J Comp Neurol
; 522(12): 2784-801, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24610493
19.
Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation.
Stem Cell Res Ther
; 4(3): 57, 2013 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23710605
20.
Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: effect on spinally grafted human neural precursor survival.
Exp Neurol
; 248: 85-99, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23748136