Detalhe da pesquisa
1.
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Nature
; 556(7699): 57-63, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512652
2.
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Nature
; 553(7687): 217-221, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29258297
3.
A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells.
Nucleic Acids Res
; 44(20): 9758-9770, 2016 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27515511
4.
Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo.
Nat Commun
; 14(1): 4928, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37582836
5.
CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells.
Curr Protoc Hum Genet
; 96: 21.11.1-21.11.20, 2018 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29364519
6.
Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.
Nat Commun
; 8: 15939, 2017 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28656978
7.
Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases.
Cell Chem Biol
; 23(1): 57-73, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26933736
8.
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
Nat Biotechnol
; 33(1): 73-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25357182
9.
Structure and mechanism of the UvrA-UvrB DNA damage sensor.
Nat Struct Mol Biol
; 19(3): 291-8, 2012 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22307053